Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan; Department of Orthopedic Surgery, Chubu Rosai Hospital, Japan Organization of Occupational Health and Safety, Nagoya, Japan.
Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan; Department of Orthopedic Surgery, Chubu Rosai Hospital, Japan Organization of Occupational Health and Safety, Nagoya, Japan.
J Clin Neurosci. 2021 Aug;90:317-324. doi: 10.1016/j.jocn.2021.06.020. Epub 2021 Jun 21.
The aim of this study was to determine age-related changes and sex-specific differences in sagittal alignment, range of motion (ROM), and intervertebral disc height of the thoracolumbar spine in healthy subjects. Lateral neutral and flexion-extension radiographs of the thoracolumbar spine of 627 asymptomatic subjects (307 males and 320 females; average age, 49.6 ± 16.5 years) were evaluated. We included at least 50 males and 50 females in each decade of life between the 20s and the 70s. Intervertebral disc height from T10/T11 to L5/S1, local lordotic alignment, and ROM from T10-T11 to L5-S1 were measured. T10-L2 kyphosis and T12-S1 lordosis as well as flexion, extension, and total ROM were measured. T10-L2 kyphosis did not markedly change with age in subjects of either sex but a sudden increase was noted in the 70s females. T12-S1 lordosis increased with age in both sexes, except the 70s. Flexion, extension, and total ROM at T10-L2 and T12-S1 decreased with age in most subjects. The levels from L3-L4 to L5-S1 were conspicuous as mobile segments. Intervertebral disc height gradually increased from T10/T11 to L4/L5; the shortest was at T10/T11 and the longest at L3/L4 or L4/L5 in all subjects. Age-related decreases in intervertebral disc height were most prominent at L4/L5 in middle-aged and elderly individuals of both sexes. Normative values of sagittal alignment, ROM, and intervertebral disc height at each segmental level were established in both sexes and all age groups in healthy subjects.
本研究旨在确定健康受试者胸腰椎矢状位排列、活动度（ROM）和椎间盘高度的年龄相关性变化和性别特异性差异。评估了 627 例无症状受试者（307 名男性和 320 名女性；平均年龄 49.6±16.5 岁）的胸腰椎侧位中立位和屈伸位 X 线片。我们在 20 多岁到 70 多岁的每个年龄段至少纳入了 50 名男性和 50 名女性。测量了 T10/T11 至 L5/S1 的椎间盘高度、局部前凸排列和 T10-T11 至 L5-S1 的 ROM。测量了 T10-L2 后凸和 T12-S1 前凸以及屈伸和总 ROM。在男性和女性受试者中，T10-L2 后凸随年龄变化不大，但在 70 多岁的女性中突然增加。T12-S1 前凸在两性中均随年龄增长而增加，70 多岁者除外。在大多数受试者中，T10-L2 和 T12-S1 的屈伸和总 ROM 随年龄增长而减少。L3-L4 至 L5-S1 水平是明显的活动节段。椎间盘高度从 T10/T11 逐渐增加到 L4/L5；在所有受试者中，最短的是 T10/T11，最长的是 L3/L4 或 L4/L5。在两性的中年和老年个体中，椎间盘高度随年龄下降最明显的是 L4/L5。在两性和所有年龄组的健康受试者中，建立了每个节段的矢状位排列、ROM 和椎间盘高度的正常值。
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