Marincolo Juliana Carvalho Segato, Aprahamian Ivan, Corona Ligiana Pires, Neri Anita Liberalesso, Yassuda Mônica Sanches, Borim Flávia Silva Arbex
Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas, Brazil.
Group of Investigation on Multimorbidity and Mental Health in Aging (GIMMA), Geriatrics Division, Jundiaí Medical School (FMJ), Jundiaí, Brazil.
Osteoporos Sarcopenia. 2021 Jun;7(2):69-74. doi: 10.1016/j.afos.2021.05.001. Epub 2021 May 25.
To assess the prevalence of probable sarcopenia according to 3 different definitions ("strength, assistance with walking, rise from a chair, climb stairs, falls"- SARC-F score, low grip strength, and the guidelines indicated by the European Working Group on Sarcopenia in Older People 2 - EWGSOP2) and assess the association of probable sarcopenia with functional disability and falls among community-dwelling older adults.
Cross-sectional study with 419 older adults. Probable sarcopenia was assessed by 3 definitions: a SARC-F ≥ 4, low grip strength (< 27 kg for men and < 16 kg for women), and the EWGSOP2 criteria. Associations were investigated using Pearson's chi-square test and prevalence ratios were estimated by Poisson regression (P < 0.05).
Of the total, probable sarcopenia was identified in 23.0% of participants (SARC-F ≥ 4 score), 33.7% (low grip strength), and 10.4% (EWGSOP2) according to each different definition. In adjusted regression models, having at least 1 instrumental activities of daily living (IADL) disability and having fallen in the last 12 months were significantly associated with a SARC-F ≥ 4 (prevalence ratio, PR = 1.60; and PR = 2.50, respectively) and EWGSOP2 (PR = 1.78; and PR = 2.19, respectively).
IADL disability and falls were associated with a SARC-F ≥ 4 and the EWGSOP2 criteria (SARC-F ≥ 4 and low grip strength). Probable sarcopenia may be used in clinical practice in order to facilitate the diagnosis of definite sarcopenia and to implement early interventions that could prevent functional decline and falls in older people.
根据3种不同定义（“力量、行走辅助、从椅子上起身、爬楼梯、跌倒”——SARC-F评分、握力低，以及老年人肌少症欧洲工作组2（EWGSOP2）所指出的指南）评估可能的肌少症患病率，并评估社区居住的老年人中可能的肌少症与功能残疾和跌倒之间的关联。
对419名老年人进行横断面研究。通过3种定义评估可能的肌少症：SARC-F≥4、握力低（男性<27千克，女性<16千克），以及EWGSOP2标准。使用Pearson卡方检验研究关联，并通过Poisson回归估计患病率比（P<0.05）。
根据每种不同定义，在全部参与者中，分别有23.0%（SARC-F≥4分）、33.7%（握力低）和10.4%（EWGSOP2）被确定为可能的肌少症。在调整后的回归模型中，至少有1项日常生活工具性活动（IADL）残疾以及在过去12个月内跌倒与SARC-F≥4（患病率比，PR分别为1.60和2.50）和EWGSOP2（PR分别为1.78和2.19）显著相关。
IADL残疾和跌倒与SARC-F≥4以及EWGSOP2标准（SARC-F≥4和握力低）相关。可能的肌少症可用于临床实践，以促进确诊肌少症的诊断，并实施可预防老年人功能衰退和跌倒的早期干预措施。
