1Division of Infectious Diseases, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas.
2Universidad Peruana Cayetano Heredia and University of Texas Medical Branch Collaborative Research Center, Cusco, Peru.
Am J Trop Med Hyg. 2021 Jul 19;105(3):684-687. doi: 10.4269/ajtmh.20-1649.
School-age children bear the highest burden of fascioliasis in endemic countries. Few studies have addressed Fasciola in preschool children. We performed a secondary data analysis using two Fasciola databases from Cusco, Peru, comparing preschoolers with elementary school children. We included 2,630 children, 50% were female, the median age was 8.4 years (interquartile range [IQR] 6.1-10.5), and 15% (396/2,630) were < 5 years of age. Children < 5 years were less likely to be infected with Fasciola hepatica (P = 0.008) and Hymenolepis nana (P < 0.001) and more likely to have anemia (P < 0.001) and a lower median height for age Z (HAZ) score (P = 0.002). Fascioliasis was less common in younger children, but this group may be at higher risk for chronic complications caused by fascioliasis.
学龄儿童在流行地区承担着肝片形吸虫病的最高负担。很少有研究涉及学龄前儿童的肝片形吸虫病。我们利用秘鲁库斯科的两个肝片形吸虫病数据库进行了二次数据分析，比较了学龄前儿童和小学生。我们纳入了 2630 名儿童，其中 50%为女性，中位年龄为 8.4 岁（四分位间距 [IQR] 6.1-10.5），15%（396/2630）年龄<5 岁。<5 岁的儿童感染肝片形吸虫（P=0.008）和细粒棘球绦虫（P<0.001）的可能性较低，贫血（P<0.001）和年龄别身高 Z 评分（HAZ）中位数较低（P=0.002）的可能性较高。年龄较小的儿童肝片形吸虫病较少见，但这一群体可能因肝片形吸虫病而面临更高的慢性并发症风险。
