Cement-retained restorations on implants ensures better passive fit and aesthetics, simplicity of fabrication and a homogenous load distribution during function, compared to screw-retained restorations, but it is associated to biological complications following the difficulty to remove cement excess. In fact, residual cement is a predisposing factor to peri-implant tissue inflammation and periimplantitis, because promotes plaque retention of bacteria, due to rough surface. This is especially true since radiographs should not reveal the cement excess and cements commonly used for the cementation of implantsupported prostheses have poor radiodensity. This report documents a case of clinical and radiographic findings of peri-implant disease associated with excess cement extrusion. Two months after cement removal, resolution of inflammation occurred. A good method of cementation, an accessible margin of restoration and the use of ZnOE cement instead of methacrylate cement, should help to prevent cementrelated peri-implant disease.