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种植体周围水泥和螺钉保留植入物的临床和影像学状况及 PISF 水平。

Clinical and Radiographic Status and PISF Levels of PGE2 Around Cement and Screw Retained Implants.

机构信息

Department of Preventive Dental Sciences, College of Dentistry, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.

Department of Preventive Dental Sciences, Faculty of Dentistry, Najran University, Najran, Saudi Arabia.

出版信息

Int Dent J. 2024 Dec;74(6):1378-1385. doi: 10.1016/j.identj.2024.04.026. Epub 2024 Jun 11.

Abstract

BACKGROUND

The aim was to assess the peri-implant clinicoradiographic status and prostaglandin E2 (PGE2) levels in peri-implant sulcular fluid (PISF) samples collected from individuals with cement-retained and crew-retained implants.

METHODS

In this observational study, participants with cement-retained and screw-retained implants were enrolled. A questionnaire was utilized to gather demographic information and assess the educational background of the participants. Peri-implant modified plaque and bleeding indices, probing depth, and crestal bone loss were measured. Subsequently, PISF samples were collected, and corresponding volumes were recorded. Commercial kits employing enzyme-linked immunosorbent assay were employed to quantify PGE2 levels. The sample size was determined, and group comparisons were conducted using the Student t test and the Mann-Whitney U-test. Logistic regression models were constructed to evaluate the correlation between PGE2 levels and clinicoradiographic and demographics. The predefined level of significance was established at P < .05.

RESULTS

Sixty-seven participants, consisting of 33 with cement-retained implants and 34 with screw-retained implants, were included in the study. The mean ages for individuals with cement and screw-retained implants were 54.2 ± 8.7 and 58.7 ± 7.4 years, respectively. The majority of participants had completed university-level education. Reportedly, 87.9% and 82.4% of individuals with cement and screw-retained implants, respectively brushed teeth twice daily. No significant differences were observed in clinicoradiographic parameters, PGE2 volume, and levels between cement-retained and screw-retained implants. There was no correlation between PGE2 levels and peri-implant clinicoradiographic parameters among individuals with either cement-retained or screw-retained implants.

CONCLUSIONS

Cement-retained and screw-retained implants exhibit a consistent peri-implant clinicoradiographic status, accompanied by stable levels of PGE2 in PISF provided oral hygiene maintenance regimens are stringently followed.

摘要

背景

本研究旨在评估固位水泥型和螺丝固位型种植体周围龈沟液(PISF)样本中的前列腺素 E2(PGE2)水平与临床影像学状况。

方法

本观察性研究纳入了固位水泥型和螺丝固位型种植体的患者。采用问卷调查的方式收集患者的人口统计学资料和背景信息。测量种植体周围改良菌斑和出血指数、探诊深度和牙槽嵴骨丧失情况。然后收集 PISF 样本,并记录相应的样本量。采用酶联免疫吸附试验的商业试剂盒来定量 PGE2 水平。根据样本量计算公式确定样本量,并采用学生 t 检验和曼-惠特尼 U 检验进行组间比较。构建逻辑回归模型来评估 PGE2 水平与临床影像学及人口统计学之间的相关性。以 P <.05 为检验水准。

结果

本研究共纳入 67 名患者,其中 33 名患者为固位水泥型种植体,34 名患者为螺丝固位型种植体。固位水泥型和螺丝固位型种植体患者的平均年龄分别为 54.2 ± 8.7 岁和 58.7 ± 7.4 岁。大多数患者均完成了大学教育。据报道,分别有 87.9%和 82.4%的固位水泥型和螺丝固位型种植体患者每天刷牙两次。固位水泥型和螺丝固位型种植体患者的临床影像学参数、PGE2 样本量和水平均无显著差异。在固位水泥型和螺丝固位型种植体患者中,PGE2 水平与种植体周围临床影像学参数之间均无相关性。

结论

在严格遵循口腔卫生维护方案的前提下,固位水泥型和螺丝固位型种植体具有一致的种植体周围临床影像学表现,并伴有稳定的 PISF 中 PGE2 水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c50/11551583/cbc07c5a683c/gr1.jpg

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