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高收入国家儿童精神障碍的患病率:一项为政策制定提供信息的系统评价和荟萃分析

Prevalence of childhood mental disorders in high-income countries: a systematic review and meta-analysis to inform policymaking.

作者信息

Barican Jenny Lou, Yung Donna, Schwartz Christine, Zheng Yufei, Georgiades Katholiki, Waddell Charlotte

机构信息

Children's Health Policy Centre, Simon Fraser University, Vancouver, British Columbia, Canada.

Offord Centre for Child Studies, McMaster University, Hamilton, Ontario, Canada.

出版信息

Evid Based Ment Health. 2022 Feb;25(1):36-44. doi: 10.1136/ebmental-2021-300277. Epub 2021 Jul 19.

Abstract

QUESTION

Mental disorders typically start in childhood and persist, causing high individual and collective burdens. To inform policymaking to address children's mental health in high-income countries we aimed to identify updated data on disorder prevalence.

METHODS

We identified epidemiological studies reporting mental disorder prevalence in representative samples of children aged 18 years or younger-including a range of disorders and ages and assessing impairment (searching January 1990 through February 2021). We extracted associated service-use data where studies assessed this. We conducted meta-analyses using a random effects logistic model (using R metafor package).

FINDINGS

Fourteen studies in 11 countries met inclusion criteria, published from 2003 to 2020 with a pooled sample of 61 545 children aged 4-18 years, including eight reporting service use. (All data were collected pre-COVID-19.) Overall prevalence of any childhood mental disorder was 12.7% (95% CI 10.1% to 15.9%; I=99.1%). Significant heterogeneity pertained to diagnostic measurement and study location. Anxiety (5.2%), attention-deficit/hyperactivity (3.7%), oppositional defiant (3.3%), substance use (2.3%), conduct (1.3%) and depressive (1.3%) disorders were the most common. Among children with mental disorders, only 44.2% (95% CI 37.6% to 50.9%) received any services for these conditions.

CONCLUSIONS

An estimated one in eight children have mental disorders at any given time, causing symptoms and impairment, therefore requiring treatment. Yet even in high-income countries, most children with mental disorders are not receiving services for these conditions. We discuss the implications, particularly the need to substantially increase public investments in effective interventions. We also discuss the policy urgency, given the emerging increases in childhood mental health problems since the onset of the COVID-19 pandemic (PROSPERO CRD42020157262).

摘要

问题

精神障碍通常始于童年并持续存在,给个人和社会带来沉重负担。为了为高收入国家制定解决儿童心理健康问题的政策提供依据,我们旨在确定关于疾病患病率的最新数据。

方法

我们确定了报告18岁及以下儿童代表性样本中精神障碍患病率的流行病学研究——包括一系列疾病和年龄,并评估损害情况(检索时间为1990年1月至2021年2月)。如果研究评估了相关服务使用情况,我们就提取这些数据。我们使用随机效应逻辑模型(使用R语言的metafor包)进行荟萃分析。

结果

11个国家的14项研究符合纳入标准,发表于2003年至2020年,汇总样本为61545名4至18岁儿童,其中8项研究报告了服务使用情况。(所有数据均在新冠疫情之前收集。)任何儿童精神障碍的总体患病率为12.7%(95%置信区间10.1%至15.9%;I² = 99.1%)。显著的异质性与诊断测量和研究地点有关。焦虑症(5.2%)、注意力缺陷/多动障碍(3.7%)、对立违抗障碍(3.3%)、物质使用障碍(2.3%)、品行障碍(1.3%)和抑郁症(1.3%)是最常见的疾病。在患有精神障碍的儿童中,只有44.2%(95%置信区间37.6%至50.9%)因这些疾病接受了任何服务。

结论

估计在任何给定时间,每八个孩子中就有一个患有精神障碍,导致出现症状和功能损害,因此需要治疗。然而,即使在高收入国家,大多数患有精神障碍的儿童也没有因这些疾病接受服务。我们讨论了其中的影响,特别是大幅增加对有效干预措施的公共投资的必要性。鉴于自新冠疫情爆发以来儿童心理健康问题不断增加,我们还讨论了政策紧迫性(国际系统评价注册库CRD42020157262)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08a9/10231629/40bf615a0e6a/ebmental-2021-300277f01.jpg

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