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邀请参与一项多中心研究，该研究旨在验证在12岁以下儿科人群脑死亡/基于神经学标准诊断程序判定死亡过程中，计算机断层扫描血管造影（CTA）和计算机断层扫描灌注成像（CTP）在确定脑循环停止方面的作用。

Invitation to participate in a multi-center study for validation of cerebral computed tomography angiography and computed tomography perfusion in the determination of cerebral circulatory arrest during brain death/death by neurological criteria diagnosis procedure in paediatric population below 12 years of age.

作者信息

Bohatyrewicz Romuald, Sołek-Pastuszka Joanna, Walas Wojciech, Sznajder Katarzyna, Falba Andrzej, Chamier-Ciemińska Katarzyna, Poncyljusz Wojciech, Dąbrowski Wojciech, Rybojad Beata, Woźniak Magdalena, Wojczal Joanna, Luchowski Piotr, Zielińska Marzena, Guziński Maciej, Sierakowska Katarzyna, Kołakowska Tamara, Serafin Zbigniew, Bartkowska-Śniatkowska Alicja, Jończyk-Potoczna Katarzyna, Kobylarz Krzysztof, Byrska-Maciejasz Elżbieta, Wyrobek Łukasz, Piotrowski Andrzej, Jurkiewicz Elżbieta, Kościesza Andrzej, Migdał Marek, Tałałaj Mariola, Jakubów Piotr, Robert Janica Jacek, Pągowska-Klimek Izabela, Brzewski Michał, Jurszewicz Paweł, Dziejowska Maria, Milewicz-Podgórska Elżbieta, Bekiesinska-Figatowska Monika, Szurowska Edyta, Owczuk Radoslaw, Kusza Krzysztof, Sawicki Marcin

机构信息

Department of Anesthesiology and Intensive Therapy, Pomeranian Medical University, Szczecin, Poland

Pediatric and Neonatal Intensive Care Unit, University Hospital in Opole, Institute of Medical Science, University of Opole, Poland

出版信息

Anaesthesiol Intensive Ther. 2021;53(2):97-102. doi: 10.5114/ait.2021.107189.

DOI:10.5114/ait.2021.107189
PMID:34284550
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10158428/
Abstract

We would like to invite paediatric intensive care units (PICU) to join our multi-center trial concerning patient population < 12 y/o and aiming at: • validation of computed tomography angiography (CTA)/computed tomography perfusion (CTP) tests for brain death/death by neurological criteria (BD/DNC) diagnosis procedures, • validation of duplex Doppler insonation of extracranial segments of the internal cerebral arteries and the vertebral arteries for choosing an optimal time for CTA/CTP testing.

摘要

我们诚邀儿科重症监护病房（PICU）参与我们的多中心试验，该试验针对12岁以下患者群体，旨在：• 验证计算机断层血管造影（CTA）/计算机断层灌注（CTP）检查在脑死亡/神经病学标准判定死亡（BD/DNC）诊断程序中的有效性，• 验证经颅多普勒超声对大脑前动脉和椎动脉颅外段的检查，以确定CTA/CTP检查的最佳时机。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1532/10158428/d85a79aecbf6/AIT-53-44487-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1532/10158428/d2a42a8e2d6f/AIT-53-44487-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1532/10158428/c7169872e784/AIT-53-44487-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1532/10158428/d85a79aecbf6/AIT-53-44487-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1532/10158428/d2a42a8e2d6f/AIT-53-44487-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1532/10158428/c7169872e784/AIT-53-44487-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1532/10158428/d85a79aecbf6/AIT-53-44487-g003.jpg

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本文引用的文献

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Determination of Brain Death/Death by Neurologic Criteria: The World Brain Death Project.脑死亡/神经标准判定死亡：世界脑死亡项目。
JAMA. 2020 Sep 15;324(11):1078-1097. doi: 10.1001/jama.2020.11586.
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Comparison of Two Apnea Test Methods, Oxygen Insufflation and Continuous Positive Airway Pressure During Diagnosis of Brain Death: Final Report.两种窒息测试方法（给氧和持续气道正压通气）在脑死亡诊断中的比较：最终报告。
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3
Computed Tomography Perfusion is a Useful Adjunct to Computed Tomography Angiography in the Diagnosis of Brain Death.
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Clin Neuroradiol. 2019 Mar;29(1):101-108. doi: 10.1007/s00062-017-0631-7. Epub 2017 Nov 17.
4
Apnea testing using the oxygen insufflation method for diagnosis of brain death may compromise pulmonary function.使用氧气吹入法进行呼吸暂停测试以诊断脑死亡可能会损害肺功能。
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