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Loss of FBXL14 promotes mesenchymal shift and radioresistance of non-small cell lung cancer by TWIST1 stabilization.

作者信息

Cui Yan-Hong, Kang Jae-Hyeok, Suh Yongjoon, Zhao Yi, Yi Joo Mi, Bae In-Hwa, Lee Hae-June, Park Dong Won, Kim Min-Jung, Lee Su-Jae

机构信息

Department of Life Science, Research Institute for Natural Sciences, Hanyang University, Seoul, Korea.

Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA.

出版信息

Signal Transduct Target Ther. 2021 Jul 21;6(1):272. doi: 10.1038/s41392-021-00599-z.

DOI:10.1038/s41392-021-00599-z
PMID:34285182
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8292372/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8227/8292372/90fe4e5fd4a0/41392_2021_599_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8227/8292372/90fe4e5fd4a0/41392_2021_599_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8227/8292372/90fe4e5fd4a0/41392_2021_599_Fig1_HTML.jpg

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本文引用的文献

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Radiation-Induced Pulmonary Epithelial-Mesenchymal Transition: A Review on Targeting Molecular Pathways and Mediators.放射性肺上皮-间充质转化:靶向分子途径和介质的综述。
Curr Drug Targets. 2018;19(10):1191-1204. doi: 10.2174/1389450119666180207092234.
2
Cancer statistics, 2018.癌症统计数据,2018 年。
CA Cancer J Clin. 2018 Jan;68(1):7-30. doi: 10.3322/caac.21442. Epub 2018 Jan 4.
3
Identification of a radiosensitivity signature using integrative metaanalysis of published microarray data for NCI-60 cancer cells.
泛素化或去泛素化修饰调控实体瘤放射敏感性的机制
Biomedicines. 2023 Dec 7;11(12):3240. doi: 10.3390/biomedicines11123240.
4
Roles of Twist1 in lipid and glucose metabolism.Twist1 在脂质和糖代谢中的作用。
Cell Commun Signal. 2023 Oct 2;21(1):270. doi: 10.1186/s12964-023-01262-6.
5
Review: Mechanisms and perspective treatment of radioresistance in non-small cell lung cancer.综述:非小细胞肺癌放射抵抗的机制和治疗视角。
Front Immunol. 2023 Feb 14;14:1133899. doi: 10.3389/fimmu.2023.1133899. eCollection 2023.
6
Phosphorylation of USP29 by CDK1 Governs TWIST1 Stability and Oncogenic Functions.CDK1 调控 USP29 对 TWIST1 稳定性及其致癌功能的影响
Adv Sci (Weinh). 2023 Apr;10(11):e2205873. doi: 10.1002/advs.202205873. Epub 2023 Feb 13.
7
Tumor-suppressive E3 ubiquitin ligase CHIP inhibits the PBK/ERK axis to repress stem cell properties and radioresistance in non-small cell lung cancer.抑癌 E3 泛素连接酶 CHIP 通过抑制 PBK/ERK 轴抑制非小细胞肺癌干细胞特性和放射抵抗。
Apoptosis. 2023 Apr;28(3-4):397-413. doi: 10.1007/s10495-022-01789-y. Epub 2022 Nov 27.
8
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