在日本，克拉霉素和西他沙星联合治疗其他微生物合并感染所致的重症肺部病例效果良好。
Severe Pulmonary s Cases Due to Co-Infection with Other Microorganisms Well Treated by Clarithromycin and Sitafloxacin in Japan.
作者信息
Takano Kazuki, Shimada Daishi, Kashiwagura Shota, Kamioka Yasuhiro, Hariu Maya, Watanabe Yuji, Seki Masafumi
机构信息
Division of Infectious Diseases and Infection Control, Faculty of Medicine.
Laboratory for Clinical Microbiology.
出版信息
Int Med Case Rep J. 2021 Jul 12;14:465-470. doi: 10.2147/IMCRJ.S321969. eCollection 2021.
BACKGROUND
frequently causes severe infections, yet its pathophysiological features and treatment regimens have not been established.
CASE REPORT
We present five cases of severe pneumonia due to infection in Japan. All cases were diabetic patients, with possible acceleration to pneumonia due to co-infection with other microorganisms. However, following a short period of hospitalization and combination therapy with intravenous imipenem/cilastatin and amikacin, all the cases were successfully treated as outpatients with oral clarithromycin and sitafloxacin.
CONCLUSION
infections can become severe in the presence of diabetes mellitus and co-infection with other chronic infectious organisms. Sitafloxacin might be a key drug in the treatment of infection in future.
背景
常引发严重感染，但其病理生理特征及治疗方案尚未明确。
病例报告
我们呈现了日本5例因感染导致的严重肺炎病例。所有病例均为糖尿病患者，可能因合并其他微生物感染而加速发展为肺炎。然而，经过短期住院治疗并联合静脉注射亚胺培南/西司他丁和阿米卡星后，所有病例均成功转为门诊治疗，口服克拉霉素和西他沙星。
结论
在糖尿病及合并其他慢性感染性生物体感染的情况下，感染可能会变得严重。西他沙星可能是未来治疗感染的关键药物。
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