Katsouras Christos, Tsivgoulis Georgios, Papafaklis Michail, Karapanayiotides Theodore, Alexopoulos Dimitrios, Ntais Evangelos, Papagiannopoulou Georgia, Koutroulou Ioanna, Ziakas Antonios, Sianos Georgios, Kouparanis Antonios, Trivilou Paraskevi, Ballas Christos, Samara Ioanna, Kosmidou Maria, Palaiodimou Lina, Grigoriadis Nikolaos, Michalis Lampros K, Giannopoulos Sotirios
Second Department of Cardiology, University Hospital of Ioannina, University of Ioannina, Ioannina, Greece.
Second Department of Neurology, ATTIKON University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Ther Adv Neurol Disord. 2021 Jul 7;14:17562864211029540. doi: 10.1177/17562864211029540. eCollection 2021.
An alarming cerebro/cardiovascular collateral damage, reflected by a decline in admissions for acute stroke (AS) and acute coronary syndrome (ACS), was observed during the initial phase of the COVID-19 pandemic, thereby leading to a re-design of public campaigns. However, there are limited data regarding the AS and ACS hospitalization rates during the second wave of the pandemic, which was followed by re-imposition of lockdowns.
We calculated the rate of AS and ACS hospitalizations from three representative tertiary care hospitals in Greece during a 2-month period (November-December 2020) of the second wave of the COVID-19 pandemic compared with the corresponding control period in 2019 from three representative tertiary care hospitals in Greece. This was a follow-up study with identical design to our previous report evaluating AS and ACS hospitalizations during the first wave of the pandemic (March-April 2020).
Compared with 2019, there was a 34% relative reduction of AS hospitalizations [incidence rate ratio (IRR): 0.66, 95% confidence interval (CI): 0.48-0.92, = 0.013] and 33% relative reduction of ACS hospitalizations (IRR: 0.67, 95% CI: 0.54-0.83, < 0.001) during the second wave of the COVID-19 pandemic. The relative reduction was smaller and did not reach the level of statistical significance for the respective syndromes (haemorrhagic stroke: IRR 0.87, 95% CI: 0.41-1.82, = 0.71; ST-elevation myocardial infarction: IRR 0.81, 95% CI: 0.57-1.14, = 0.22).
AS and ACS hospitalizations were persistently reduced during the second wave of the COVID-19 pandemic compared with 2019 in Greece. This decline was similar to the observations during the first wave despite the large differences in the epidemiological COVID-19 burden. Lockdowns, a common characteristic in both waves, appear to have a detrimental indirect impact on cerebro/cardiovascular diseases in the general population.
在新冠疫情的初始阶段，观察到急性中风（AS）和急性冠状动脉综合征（ACS）入院人数下降，这反映出令人担忧的脑/心血管附带损害，从而导致公共宣传活动重新设计。然而，关于疫情第二波期间AS和ACS住院率的数据有限，第二波疫情之后重新实施了封锁措施。
我们计算了希腊三家代表性三级医疗机构在新冠疫情第二波期间（2020年11月至12月）为期2个月的AS和ACS住院率，并与2019年希腊三家代表性三级医疗机构相应的对照期进行比较。这是一项随访研究，其设计与我们之前评估疫情第一波期间（2020年3月至4月）AS和ACS住院情况的报告相同。
与2019年相比，在新冠疫情第二波期间，AS住院率相对降低了34%[发病率比值（IRR）：0.66，95%置信区间（CI）：0.48 - 0.92，P = 0.013]，ACS住院率相对降低了33%（IRR：0.67，95% CI：0.54 - 0.83，P < 0.001）。对于各自的综合征（出血性中风：IRR 0.87，95% CI：0.41 - 1.82，P = 0.71；ST段抬高型心肌梗死：IRR 0.81，95% CI：0.57 - 1.14，P = 0.22），相对降低幅度较小且未达到统计学显著水平。
与2019年相比，希腊在新冠疫情第二波期间AS和ACS住院率持续降低。尽管两波疫情期间新冠病毒流行负担差异很大，但这种下降与第一波期间的观察结果相似。封锁措施是两波疫情的共同特征，似乎对普通人群的脑/心血管疾病产生了有害的间接影响。
Zotero 插件
