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与 COVID-19 爆发期间希腊的急性冠状动脉综合征相比,急性脑卒中入院人数下降更多:第二波浪潮中的脑/心血管影响。

Greater decline of acute stroke admissions compared with acute coronary syndromes during COVID-19 outbreak in Greece: Cerebro/cardiovascular implications amidst a second wave surge.

机构信息

2nd Department of Cardiology, University Hospital of Ioannina, University of Ioannina, Ioannina, Greece.

2nd Department of Neurology, Faculty of Health Sciences, School of Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.

出版信息

Eur J Neurol. 2021 Oct;28(10):3452-3455. doi: 10.1111/ene.14666. Epub 2020 Dec 27.

DOI:10.1111/ene.14666
PMID:33290619
Abstract

BACKGROUND AND PURPOSE

A remarkable decline in admissions for acute stroke and acute coronary syndrome (ACS) has been reported in countries severely hit by the COVID-19 pandemic. However, limited data are available from countries with less COVID-19 burden focusing on concurrent stroke and ACS hospitalisation rates from the same population.

METHODS

The study was conducted in three geographically and demographically representative COVID-19 referral university hospitals in Greece. We recorded the rate of stroke and ACS hospital admissions during a 6-week period of the COVID-19 outbreak in 2020 and compared them with the rates of the corresponding period in 2019.

RESULTS

We found a greater relative reduction of stroke admissions (51% [35 vs. 71]; incidence rate ratio [IRR]: 0.49, p = 0.001) compared with ACS admissions (27% [123 vs. 168]; IRR: 0.73, p = 0.009) during the COVID-19 outbreak (p = 0.097). Fewer older (>65 years) patients (stroke: 34.3% vs. 45.1%, odds ratio [OR]: 0.64, p = 0.291; ACS: 39.8% vs. 54.2%, OR: 0.56, p = 0.016) were admitted during the COVID-19 compared with the control period.

CONCLUSIONS

Hospitalisation rates both for stroke and ACS were reduced during the COVID-19 outbreak in a country with strict social distancing measures, low COVID-19 incidence and low population mortality. Lack of triggers for stroke and ACS during social distancing/quarantining may explain these observations. However, medical care avoidance attitudes among cerebro/cardiovascular patients should be dissipated amidst the rising second COVID-19 wave.

摘要

背景与目的

在受 COVID-19 大流行严重打击的国家,报告了急性中风和急性冠状动脉综合征 (ACS) 的住院人数显著下降。然而,来自 COVID-19 负担较低的国家的数据有限,这些国家重点关注同一人群中中风和 ACS 的住院率。

方法

本研究在希腊的三家具有地理和人口代表性的 COVID-19 转诊大学医院进行。我们记录了 2020 年 COVID-19 爆发期间的中风和 ACS 住院人数,并将其与 2019 年同期的人数进行了比较。

结果

我们发现,与 ACS 住院人数相比,COVID-19 爆发期间中风住院人数的相对减少幅度更大(51% [35 例比 71 例];发病率比 [IRR]:0.49,p=0.001)。在 COVID-19 期间,年龄较大(>65 岁)患者(中风:34.3%比 45.1%,比值比 [OR]:0.64,p=0.291;ACS:39.8%比 54.2%,OR:0.56,p=0.016)的住院人数减少。

结论

在严格的社会隔离措施、低 COVID-19 发病率和低人口死亡率的国家,COVID-19 爆发期间中风和 ACS 的住院率均下降。在社会隔离/检疫期间,中风和 ACS 缺乏触发因素可能解释了这些观察结果。然而,在第二波 COVID-19 浪潮中,应消除脑/心血管患者对医疗保健的回避态度。

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