Langendijk Johannes A, Hoebers Frank J P, de Jong Martin A, Doornaert Patricia, Terhaard Chris H J, Steenbakkers Roel J H M, Hamming-Vrieze Olga, van de Kamer Jeroen B, Verbakel Wilko F A R, Keskin-Cambay Fatma, Reitsma Johannes B, van der Schaaf Arjen, Boersma Liesbeth J, Schuit Ewoud
Department of Radiation Oncology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.
Department of Radiation Oncology (MAASTRO clinic), GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, the Netherlands.
Int J Part Ther. 2021 Jun 25;8(1):354-365. doi: 10.14338/IJPT-20-00089.1. eCollection 2021 Summer.
In the Netherlands, the model-based approach is used to identify patients with head and neck cancer who may benefit most from proton therapy in terms of prevention of late radiation-induced side effects in comparison with photon therapy. To this purpose, a National Indication Protocol Proton therapy for Head and Neck Cancer patients (NIPP-HNC) was developed, which has been approved by the health care authorities. When patients qualify according to the guidelines of the NIPP-HNC, proton therapy is fully reimbursed. This article describes the procedures that were followed to develop this NIPP-HNC and provides all necessary information to introduce model-based selection for patients with head and neck cancer into routine clinical practice.
在荷兰,基于模型的方法用于识别头颈癌患者,这些患者与光子治疗相比,在预防晚期辐射诱发副作用方面可能从质子治疗中获益最多。为此,制定了一项针对头颈癌患者的国家质子治疗适应症协议(NIPP-HNC),该协议已获得医疗保健当局的批准。当患者符合NIPP-HNC的指导方针时,质子治疗可全额报销。本文描述了制定该NIPP-HNC所遵循的程序,并提供了将基于模型的头颈癌患者选择方法引入常规临床实践所需的所有信息。