Department of Epidemiology, Ministry of Education Key Laboratory of Public Health Safety, Fudan School of Public Health, Shanghai, China.
Department of Immunization Planning, Minhang District Center for Disease Control and Prevention, Shanghai, China.
Expert Rev Vaccines. 2021 Sep;20(9):1147-1152. doi: 10.1080/14760584.2021.1954910. Epub 2021 Jul 21.
Vaccination uptake of influenza vaccine, 23-valent pneumococcal polysaccharide vaccine (PPV23) and herpes zoster vaccine (HZV) remains low among Chinese aged 50-69 years, posing a significant public health concern. This study's aim is to determine the gap between the vaccination willingness and uptake.
We conducted a face-to-face questionnaire survey among the persons aged 50-69 years in 13 communities in Shanghai in November-December 2020 to measure vaccination willingness, vaccine price sensitivity, vaccination service accessibility, and vaccine hesitancy. Then, we explored the factors influencing the vaccination uptake using a structural equation model.
Vaccination willingness was 70.5% (self-paid influenza vaccine), 79.4% (free PPV23 for local persons), 54.7% (self-paid PPV23 for non-local persons), and 16.6% (self-paid HZV); however, actual uptake was 10.8% (influenza vaccine), 11.0% (free PPV23), and 2.5% (self-paid PPV23). Moreover, vaccination uptake was strongly influenced by service accessibility (β = 0.941), followed by willingness (β = 0.201), price sensitivity (β = -0.188), and medical history of vaccine-preventable diseases and underlying diseases (β = 0.176). Related knowledge (β = 0.017) and vaccine hesitancy (β = -0.003) affected the uptake indirectly.
There is a gap between the vaccination willingness and uptake in Chinese elderly. It warrants specific measures, including increasing service accessibility and reforming payment mechanism, to bridge the gap.
在中国 50-69 岁人群中,流感疫苗、23 价肺炎球菌多糖疫苗(PPV23)和带状疱疹疫苗(HZV)的接种率仍然较低,这对公共卫生构成了重大威胁。本研究旨在确定接种意愿和接种率之间的差距。
我们于 2020 年 11 月至 12 月在上海的 13 个社区对 50-69 岁人群进行了面对面的问卷调查,以衡量接种意愿、疫苗价格敏感度、疫苗接种服务可及性和疫苗犹豫情况。然后,我们使用结构方程模型探讨了影响接种率的因素。
接种意愿分别为 70.5%(自费流感疫苗)、79.4%(本地居民免费 PPV23)、54.7%(非本地居民自费 PPV23)和 16.6%(自费 HZV);但实际接种率分别为 10.8%(流感疫苗)、11.0%(免费 PPV23)和 2.5%(自费 PPV23)。此外,接种率受服务可及性(β=0.941)的强烈影响,其次是意愿(β=0.201)、价格敏感度(β=-0.188)和疫苗可预防疾病和潜在疾病的医疗史(β=0.176)。相关知识(β=0.017)和疫苗犹豫(β=-0.003)间接影响接种率。
中国老年人的接种意愿和接种率之间存在差距。需要采取具体措施,包括增加服务可及性和改革支付机制,以缩小差距。