Tripathi Y, Mukhopadhyay A
Department of Physiology, Banaras Hindu University, Varanasi.
Indian J Physiol Pharmacol. 1987 Jul-Sep;31(3):190-8.
The effect of prolactin secreted from pituitary homografts under renal capsule of castrated young male rats (30 days old) either alone or in combination with testosterone propionate (TP) on accessory sex organs were studied. Fresh weights of seminal vesicle, prostate coagulating glands and preputial glands were recorded as well as the total protein content and acid phosphatase activity in prostate and seminal vesicle was determined. Prolactin secreted from grafted tissue along or in combination with TP significantly increased the weights of sex accessories but no clear synergism was evident. However, synergism between prolactin and TP was observed in stimulating protein content and acid phosphatase activity of prostate and seminal vesicle. The results indicate that prolactin can act directly and also synergistically with androgen to maintain certain aspects of the functions of accessory sex glands in male rats.
研究了阉割的30日龄年轻雄性大鼠肾囊下垂体移植组织单独分泌的催乳素或与丙酸睾酮（TP）联合分泌的催乳素对附属性器官的影响。记录了精囊、前列腺凝腺和包皮腺的鲜重，并测定了前列腺和精囊中的总蛋白含量及酸性磷酸酶活性。移植组织单独分泌的催乳素或与TP联合分泌的催乳素显著增加了性附属器官的重量，但未观察到明显的协同作用。然而，在刺激前列腺和精囊的蛋白含量及酸性磷酸酶活性方面，观察到了催乳素与TP之间的协同作用。结果表明，催乳素可直接发挥作用，也可与雄激素协同作用，以维持雄性大鼠附属性腺功能的某些方面。
