垂体移植后成年雄性大鼠附属生殖器官的酸性磷酸酶活性和新鲜组织重量
Acid phosphatase activity and fresh tissue weights of accessory sex organs in adult male rats following pituitary transplantation.
作者信息
Tripathi Y, Mukhopadhyay A K
机构信息
Department of Physiology, Banaras Hindu University, Varanasi.
出版信息
Indian J Physiol Pharmacol. 1988 Oct-Dec;32(4):271-7.
The effect of female pituitary transplantation under renal capsule of castrated adult male rats on accessory sex organs was studied either in presence or in absence of testosterone. Acid phosphatase activity in prostate and seminal vesicle was estimated apart from recording the fresh tissue weights of prostate, seminal vesicle, coagulating and preputial glands. Prolactin secreted from grafted pituitary significantly increased the fresh tissue weights of all sex accessories except seminal vesicle. Testosterone treatment in presence of pituitary graft stimulated the acid phosphatase activity of prostate and seminal vesicle. Prolactin in absence of testosterone could not change the enzymatic activity of prostate and seminal vesicle. The results indicate that prolactin can act directly on prostate, coagulating glands and preputial glands. Accessory sex organs also require the presence of androgens as well as prolactin to maintain the functions of sex accessories in adult male rats.
研究了成年去势雄性大鼠肾囊下雌性垂体移植对附属生殖器官的影响，实验分有睾酮和无睾酮两种情况进行。除记录前列腺、精囊、凝固腺和包皮腺的新鲜组织重量外，还测定了前列腺和精囊中的酸性磷酸酶活性。移植垂体分泌的催乳素显著增加了除精囊外所有性附属器官的新鲜组织重量。垂体移植存在时给予睾酮治疗可刺激前列腺和精囊的酸性磷酸酶活性。无睾酮时催乳素不能改变前列腺和精囊的酶活性。结果表明，催乳素可直接作用于前列腺、凝固腺和包皮腺。附属生殖器官还需要雄激素和催乳素的共同存在来维持成年雄性大鼠性附属器官的功能。
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