National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Nanwei road No.29, Xicheng district, Beijing, 100050, China.
Sci Rep. 2021 Jul 22;11(1):15016. doi: 10.1038/s41598-021-94375-2.
Low birth weight (< 2500 g; LBW) and macrosomia (> 4000 g) are both adverse birth outcomes with high health risk in short- or long-term period. However, national prevalence estimates of LBW and macrosomia varied partially due to methodology limits in China. The aim of this study is to estimate the prevalence of LBW and macrosomia after taking potential birth weight heaping into consideration in Chinese children under 6 years in 2013. The data were from a nationally representative cross-sectional survey in mainland China in 2013, which consists of 32,276 eligible records. Birth weight data and socio-demographic information was collected using standard questionnaires. Birth weight distributions were examined and LBW and macrosomia estimates were adjusted for potential heaping. The overall prevalence of LBW of Chinese children younger than 6 years was 5.15% in 2013, with 4.57% in boys and 5.68% in girls. LBW rate was higher for children who were minority ethnicity, had less educated mothers, mothers aged over 35 years or under 20 years, or were in lower income household than their counterparts. The overall prevalence of macrosomia of Chinese children younger than 6 years was 7.35% in 2013, with 8.85% in boys and 5.71% in girls. The prevalence of macrosomia increased with increasing maternal age, educational level and household income level. Both LBW and macrosomia varied among different regions and socio-economic groups around China. It is found that estimates based on distribution adjustment might be more accurate and could be used as the foundation for policy-decision and health resource allocation. It would be needed to take potential misclassification of birth weight data arising from heaping into account in future studies.
低出生体重(<2500 克;LBW)和巨大儿(>4000 克)都是不良的出生结局,在短期或长期都会带来较高的健康风险。然而,由于中国方法学的局限性,LBW 和巨大儿的全国流行率估计值存在差异。本研究旨在考虑潜在出生体重堆积的影响后,估计 2013 年中国 6 岁以下儿童 LBW 和巨大儿的流行率。数据来自于 2013 年中国内地一项具有全国代表性的横断面调查,共纳入 32276 例合格记录。使用标准问卷收集了出生体重数据和社会人口学信息。检查了出生体重分布情况,并对潜在堆积进行了调整,以估计 LBW 和巨大儿的发生率。2013 年中国 6 岁以下儿童 LBW 的总发生率为 5.15%,男孩为 4.57%,女孩为 5.68%。少数民族、母亲受教育程度较低、母亲年龄在 35 岁以上或 20 岁以下、家庭收入较低的儿童 LBW 发生率较高。2013 年中国 6 岁以下儿童巨大儿的总发生率为 7.35%,男孩为 8.85%,女孩为 5.71%。巨大儿的发生率随着母亲年龄、教育程度和家庭收入水平的增加而增加。LBW 和巨大儿在不同地区和社会经济群体中存在差异。研究发现,基于分布调整的估计可能更准确,可以作为政策决策和卫生资源配置的基础。未来的研究需要考虑到由于堆积而导致的出生体重数据的潜在分类错误。