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忍冬属植物中环烯醚萜苷类化学成分及药理活性的研究进展

[Research progress on chemical constituents and pharmacological activities of iridoid glycosides in Lonicera japonica].

作者信息

Yang Ran, Lu Yuan, Hao Hao, Zhang Man-da, Xuan Jing, Zhang Yong-Qing

机构信息

College of Pharmacy, Shandong University of Traditional Chinese Medicine Ji'nan 250000, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2021 Jun;46(11):2746-2752. doi: 10.19540/j.cnki.cjcmm.20210108.602.

Abstract

As a traditional Chinese medicinal material, Lonicera japonica has a long medicinal history. The chemical constituents of Lonicera japonica are complex, mainly including iridoid glycosides, flavonoids, triterpenes, organic acids and volatile oil. Iridoid glycosides account for a higher proportion. In addition, modern pharmacological studies have shown that the iridoid glycosides have many pharmacological activities such as antivirus, anti-inflammation, anti-tumor, liver protection and lowering blood sugar. This review intends to systematically summarize the iridoid glycosides identified from Lonicera japonica and their pharmacological activities by searc-hing Chinese and English databases, in order to provide a reference for the further development and utilization of Lonicera japonica and for the improvement of quality standards of medicinal materials.

摘要

金银花作为一种传统中药材,有着悠久的药用历史。金银花的化学成分复杂,主要包括环烯醚萜苷、黄酮类、三萜类、有机酸和挥发油等。其中环烯醚萜苷所占比例较高。此外,现代药理研究表明,环烯醚萜苷具有抗病毒、抗炎、抗肿瘤、保肝和降血糖等多种药理活性。本文通过检索中英文数据库,旨在系统总结从金银花中鉴定出的环烯醚萜苷及其药理活性,为金银花的进一步开发利用以及药材质量标准的提高提供参考。

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