Key Laboratory of Coastal Biology and Bioresource Utilization, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China.
Center for Ocean Mega-Science, Chinese Academy of Sciences, 7 Nanhai Road, Qingdao 266071, China.
Molecules. 2021 Jul 12;26(14):4238. doi: 10.3390/molecules26144238.
Recent years have seen a steady increase in interest and demand for the use of humectants based on biodegradable natural polymers in many fields. The aim of this paper is to investigate the moisture absorption and retention properties of 2-hydroxypropyltrimethyl ammonium chitosan derivatives which were modified by anionic compounds via ion exchange. FTIR, H NMR, and C NMR spectroscopy were used to demonstrate the specific structures of chitosan derivatives. The degrees of substitution for objective products were calculated by the integral ratio of hydrogen atoms according to H NMR spectroscopy. Meanwhile, moisture absorption of specimens was assayed in a desiccator at different relative humidity (RH: 43% and 81%), and all target products exhibited enhanced moisture absorption. Furthermore, moisture retention measurement at different relative humidity (RH: 43%, 81%, and drier silica gel) was estimated, and all target products possessed obviously improved moisture retention property. Specifically, after 48 h later, the moisture retention property of HACBA at 81% RH was 372.34%, which was much higher than HA (180.04%). The present study provided a novel method to synthesize chitosan derivatives with significantly improved moisture absorption and retention properties that would serve as potential humectants in biomedical, food, medicine, and cosmetics fields.
近年来，基于可生物降解天然聚合物的吸湿剂在许多领域的应用引起了人们的浓厚兴趣和需求。本文旨在研究通过离子交换改性的阴离子化合物的 2-羟丙基三甲基氯化铵壳聚糖衍生物的吸湿和保湿性能。傅里叶变换红外光谱（FTIR）、核磁共振氢谱（1H NMR）和 13C NMR 光谱用于证明壳聚糖衍生物的特定结构。根据 1H NMR 光谱，通过氢原子的积分比计算目标产物的取代度。同时，在不同相对湿度（RH：43%和 81%）的干燥器中测定了样品的吸湿性能，所有目标产物均表现出增强的吸湿性能。此外，还评估了不同相对湿度（RH：43%、81%和更干燥的硅胶）下的保湿性能测量，所有目标产物均具有明显改善的保湿性能。具体而言，在 81%RH 下，HACBA 在 48 小时后的保湿性能为 372.34%，远高于 HA（180.04%）。本研究提供了一种合成具有显著改善的吸湿和保湿性能的壳聚糖衍生物的新方法，可为生物医学、食品、医药和化妆品领域的潜在保湿剂提供参考。
