血液透析和腹膜透析——与健康相关的生活质量：系统评价及荟萃分析

Hemodialysis and peritoneal dialysis-health-related quality of life: systematic review plus meta-analysis.

作者信息

Raoofi Samira, Pashazadeh Kan Fatemeh, Rafiei Sima, Hoseinipalangi Zahra, Rezaei Sepide, Ahmadi Saba, Masoumi Maryam, Noorani Mejareh Zahra, Roohravan Benis Mahshid, Sharifi Alireza, Shabaninejad Hosein, Kiaee Zahra Mansour, Ghashghaee Ahmad

机构信息

Student Research Committee, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran (the Islamic Republic of).

Health Management and Economics Research Center, Health Management Research Institute, Iran University of Medical Sciences, Tehran, Iran.

出版信息

BMJ Support Palliat Care. 2023 Dec;13(4):365-373. doi: 10.1136/bmjspcare-2021-003182. Epub 2021 Jul 22.

DOI:10.1136/bmjspcare-2021-003182

PMID:34301643

Abstract

BACKGROUND

Patients with end-stage renal disease undergoing haemodialysis experience a variety of stressors leading to decreased level of quality of life (QoL). Thus, in this study, we aimed to review the current literature and identify factors affecting the health-related QoL (HRQoL) in these patients.

METHODS

A total of 147 studies were extracted from databases of Web of Science, PubMed, Scopus, Google Scholar, and Embase published between January 2000 and December 2020. Data were analysed using R software and results were reported with reference to Preferred Reporting Items for Systematic Reviews and Meta-Analyses standards.

RESULTS

A total of 623 728 patients undergoing dialysis participated in 147 studies in which QoL was assessed by means of two valid questionnaires, including Short-Form 36 (SF-36) and Kidney Disease Quality of Life (KDQOL)-short form V.1.3. Total HRQoL score for patients undergoing dialysis measured by KDQOL was 64.25 (95% CI 55.67 to 72.82). Based on SF-36, the mean score of mental health items was higher than the mean score of physical health condition. Furthermore, meta-regression based on the geographical place of residence revealed that the highest QoL in patients was observed in Japan, 66.96 (95% CI 63.65 to 70.28) and Brazil, 58.03 (95% CI 53.45 to 62.6).

CONCLUSION

Studies conducted on HRQoL among patients undergoing dialysis recommend useful strategies to clinicians, letting them assess patients' QoL in terms of a wide range of physical, mental and environmental aspects.

摘要

背景

接受血液透析的终末期肾病患者会经历各种压力源，导致生活质量（QoL）水平下降。因此，在本研究中，我们旨在回顾当前文献，并确定影响这些患者健康相关生活质量（HRQoL）的因素。

方法

从科学网、PubMed、Scopus、谷歌学术和Embase数据库中提取了2000年1月至2020年12月发表的共147项研究。使用R软件对数据进行分析，并根据系统评价和Meta分析的首选报告项目标准报告结果。

结果

共有623728名接受透析的患者参与了147项研究，其中通过两种有效问卷评估生活质量，包括简短健康调查问卷（SF-36）和肾脏疾病生活质量简表（KDQOL）-简表V.1.3。通过KDQOL测量的透析患者总HRQoL评分为 64.25（95%置信区间55.67至72.82）。基于SF-36，心理健康项目的平均得分高于身体健康状况的平均得分。此外，基于居住地理位置的Meta回归显示，患者生活质量最高的是日本，为66.96（95%置信区间63.65至70.28），以及巴西，为58.03（95%置信区间53.45至62.6）。