Winter L, Bass E, Recant B, Cahaly J F
Oral Surg Oral Med Oral Pathol. 1978 Feb;45(2):159-66. doi: 10.1016/0030-4220(78)90079-8.
The effectiveness of 400 and 800 mg. of ibuprofen was compared to that of 650 mg. of aspirin, 65 mg. of propoxyphene HCl, and placebo in 510 patients experiencing pain subsequent to oral surgical procedures. In double-blind study, patients were randomly assigned to one of five experimental groups and instructed to report the intensity of pain (complete, partial, or none) over a 3-hour period of evaluation. Ibuprofen, at both doses, was shown to be more effective for both degree and duration of relief from pain.
在510名口腔外科手术后疼痛的患者中，比较了400毫克和800毫克布洛芬与650毫克阿司匹林、65毫克盐酸丙氧芬及安慰剂的疗效。在双盲研究中，患者被随机分配到五个实验组之一，并被要求报告在3小时评估期内的疼痛强度（完全缓解、部分缓解或无缓解）。两种剂量的布洛芬在缓解疼痛的程度和持续时间上均显示出更有效。
