Sankara Eye Hospital, Shimoga, Karnataka, India.
Indian J Ophthalmol. 2021 Aug;69(8):2060-2063. doi: 10.4103/ijo.IJO_35_21.
To assess the posterior corneal elevation (PCE) in children with vernal keratoconjunctivitis (VKC) and compare the same with that of age and gender-matched normal children.
This was a case control study. We included 110 children attending the Pediatric ophthalmology outpatient department of a tertiary eye care center in South India between September 2019 and June 2020. Fifty-five children with VKC and 55 normal age and gender-matched children were examined by Sirius tomographer/topographer (CSO, Italy) to determine the PCE, thinnest corneal thickness (TCT), simulated K (Sim K), keratoconus front (KVf) and keratoconus vertex back (KVb). The parameters were compared between the two groups.
A total of 220 eyes of 110 children were examined. The mean age in both groups was 10.44 ± 3.28 years, each group included 44 males and 11 females. There was no statistically significant difference in TCT and Sim K between the two groups. The mean PCE was 18.8 ± 8.4 μm in VKC group and 11.7 ± 3.9 μm in control group (P < 0.001). Both KVf and KVb were significantly higher in VKC group when compared to the control group.
Children with VKC have significantly higher PCE as measured by Sirius tomographer, and hence, all VKC children should be screened for development of KC and the Sirius tomographer may be an appropriate tool for the same.
评估春季角结膜炎(VKC)患儿的后角膜高度(PCE),并与年龄和性别相匹配的正常儿童进行比较。
这是一项病例对照研究。我们纳入了 2019 年 9 月至 2020 年 6 月期间在印度南部一家三级眼科护理中心儿科眼科门诊就诊的 110 名儿童。使用 Sirius 断层扫描仪/地形仪(CSO,意大利)检查 55 名 VKC 患儿和 55 名年龄和性别相匹配的正常儿童,以确定 PCE、最薄角膜厚度(TCT)、模拟 K(Sim K)、圆锥角膜前缘(KVf)和圆锥角膜顶点后缘(KVb)。比较两组间的参数。
共检查了 110 名儿童的 220 只眼。两组的平均年龄均为 10.44 ± 3.28 岁,每组包括 44 名男性和 11 名女性。两组间 TCT 和 Sim K 无统计学差异。VKC 组的平均 PCE 为 18.8 ± 8.4μm,对照组为 11.7 ± 3.9μm(P<0.001)。与对照组相比,VKC 组的 KVf 和 KVb 均显著升高。
通过 Sirius 断层扫描仪测量,VKC 患儿的 PCE 明显更高,因此所有 VKC 患儿均应筛查是否发生 KC,而 Sirius 断层扫描仪可能是一种合适的筛查工具。