Department of Ophthalmology, Assaf Harofeh Medical Center, Israel.
J Refract Surg. 2012 Jul;28(7):493-7. doi: 10.3928/1081597X-20120619-01.
To assess measurement repeatability of corneal curvature, minimal corneal thickness, and anterior chamber depth obtained with the Sirius imaging system (Costruzioni Strumenti Oftalmici) and to assess its agreement with the Pentacam HR imaging system (Oculus Optikgeräte GmbH).
Healthy individuals were prospectively recruited. To assess repeatability, eight consecutive measurements were performed in the right eye of healthy individuals with the Sirius. A single measurement was then performed consecutively with both systems. The anterior and posterior corneal radii (antR and posR, respectively), anterior chamber depth, and minimal corneal thickness were evaluated. Repeatability of Sirius was evaluated by calculating coefficients of variation (CoV). Agreement between Sirius and Pentacam was assessed by calculating 95% limits of agreement (LoA) and plotting Bland-Altman graphs.
Forty-five eyes from individuals (21 men, 24 women) aged 20 to 61 years were evaluated. The mean CoV was 0.37% and 1.32% for antR and posR at 3 mm, respectively, and 0.36% and 1.28% for antR and posR at 7 mm, respectively. For anterior chamber depth and minimal corneal thickness, the CoV was 0.56% and 1.69%, respectively. Calculated 95% LoA were -0.1 to 0.12 mm (mean difference: 0.018 mm) and -0.54 to 0.33 mm (mean difference: 0.1 mm) for antR and posR at 3 mm, respectively. For anterior chamber depth, 95% LoA was -0.23 to 0.09 mm (mean difference: 0.068 mm) and -9.61 to 33.44 μm (mean difference: 11.91 μm) for minimal corneal thickness.
The Sirius showed good to excellent repeatability for all measured parameters. Agreement analysis suggests that Sirius and Pentacam should not be used interchangeably.
评估 Sirius 成像系统（Costruzioni Strumenti Oftalmici）测量角膜曲率、最小角膜厚度和前房深度的可重复性，并评估其与 Pentacam HR 成像系统（Oculus Optikgeräte GmbH）的一致性。
前瞻性招募健康个体。为了评估可重复性，在健康个体的右眼上连续进行了 8 次 Sirius 测量，然后连续使用两种系统进行了单次测量。评估了前、后角膜曲率半径（antR 和 posR）、前房深度和最小角膜厚度。通过计算变异系数（CoV）来评估 Sirius 的可重复性。通过计算 95%一致性界限（LoA）和绘制 Bland-Altman 图来评估 Sirius 和 Pentacam 的一致性。
评估了 45 只来自 20 至 61 岁个体（21 名男性，24 名女性）的眼睛。在 3mm 时，antR 和 posR 的平均 CoV 分别为 0.37%和 1.32%，在 7mm 时，antR 和 posR 的平均 CoV 分别为 0.36%和 1.28%。对于前房深度和最小角膜厚度，CoV 分别为 0.56%和 1.69%。在 3mm 时，antR 和 posR 的计算 95%LoA 分别为-0.1 至 0.12mm（平均差值：0.018mm）和-0.54 至 0.33mm（平均差值：0.1mm）。对于前房深度，95%LoA 为-0.23 至 0.09mm（平均差值：0.068mm）和-9.61 至 33.44μm（平均差值：11.91μm）。
Sirius 对所有测量参数均表现出良好到极好的可重复性。一致性分析表明， Sirius 和 Pentacam 不应互换使用。
