Luo S Y, Ye Y X, Sun M Y, Shen J C, Chen N X, Jia S, Li X Y, Liu Y H, Zhu W, Xia M
School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Department of Basic Public Health Service, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2021 Jul 6;55(7):853-859. doi: 10.3760/cma.j.cn112150-20210204-00125.
To explore the relationship of sleep quality and sleep duration with hypertension among adults aged 30-79 years old in Guangzhou. According to multi-stage stratified cluster sampling, 12 747 residents aged 30-79 years old were sampled and surveyed in Guangzhou from January 2018 to March 2019. Data on general demographic characteristics, sleep quality, sleep duration and hypertension were collected through questionnaire survey, the Pittsburgh sleep quality index (PSQI) and physical examination. Multivariate logistic regression models were used to analyze the putative association between sleep quality, sleep duration and hypertension. Restrictive cubic spline curve was used to draw the dose-response relationship curve between sleep quality, sleep time and hypertension. The mean age of the subjects was (52.68±12.17) years, the prevalence of hypertension was 36.6% (4 664/12 747), the average score of PSQI was (4.70±2.88), and the average sleep time was (7.00±1.32) hours. The prevalence of hypertension was positively associated with the PSQI score. Compared to the subjects with a score less than 3, (95%) of hypertension with a PSQI score of 3-5, 5-8, ≥9 were 1.14 (1.02-1.27), 1.17 (1.03-1.34), 1.41 (1.21-1.64), respectively. The relationship between sleep duration and hypertension appeared U-shaped. Compared with 6 to 8 hours sleep duration, both sleep duration<6 hours with (95%) of 1.27(1.12-1.43) or >8 hours with (95%) of 1.20(1.05-1.38) was associated with hypertension. Both poor sleep quality, longer or shorter sleep duration were responsible for increased risk of cognitive impairment in older Chinese.
为探讨广州市30-79岁成年人睡眠质量和睡眠时间与高血压之间的关系。按照多阶段分层整群抽样方法，于2018年1月至2019年3月在广州市抽取12747名30-79岁居民进行调查。通过问卷调查、匹兹堡睡眠质量指数（PSQI）和体格检查收集一般人口学特征、睡眠质量、睡眠时间和高血压相关数据。采用多因素logistic回归模型分析睡眠质量、睡眠时间与高血压之间的假定关联。采用限制性立方样条曲线绘制睡眠质量、睡眠时间与高血压之间的剂量反应关系曲线。受试者平均年龄为（52.68±12.17）岁，高血压患病率为36.6%（4664/12747），PSQI平均得分为（4.70±2.88），平均睡眠时间为（7.00±1.32）小时。高血压患病率与PSQI得分呈正相关。与PSQI得分小于3分的受试者相比，PSQI得分3-5分、5-8分、≥9分的高血压患者（95%）分别为1.14（1.02-1.27）、1.17（1.03-1.34）、1.41（1.21-1.64）。睡眠时间与高血压之间呈U型关系。与睡眠时间6至8小时相比，睡眠时间<6小时（95%）为1.27（1.12-1.43）或>8小时（95%）为1.20（1.05-1.38）均与高血压相关。睡眠质量差、睡眠时间过长或过短均会增加中国老年人认知障碍的风险。
