Lu Kai, Ding Rongjing, Tang Qin, Chen Jia, Wang Li, Wang Changying, Wu Shouling, Hu Dayi
Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Heart Center, Peking University People's Hospital, No.11 South Xizhimen Avenue, Beijing 100044, China.
Int J Environ Res Public Health. 2015 Jan 7;12(1):488-503. doi: 10.3390/ijerph120100488.
Assessment of sleep only by sleep duration is not sufficient. This cross-sectional study aimed to investigate the potential association of self-reported global sleep status, which contained both qualitative and quantitative aspects, with hypertension prevalence in Chinese adults.
A total of 5461 subjects (4076 of them were male) were enrolled in the current study and were divided into two groups with the age of 45 years as the cut-off value. Sleep status of all subjects was assessed using the standard Pittsburgh Sleep Quality Index (PSQI). Hypertension was defined as blood pressure ≥140/90 mmHg in the current study.
After adjusting for basic cardiovascular characteristics, the results of multivariate logistic regression indicated that sleep status, which was defined as the additive measurement of sleep duration and sleep quality, was associated with hypertension prevalence in males of both age groups (odds ratio (OR) = 1.11, 95% confidence interval (CI), 1.07-1.15, p < 0.05; OR = 1.12, 95% CI, 1.08-1.15, p < 0.05) and in females aged ≤45years (OR = 1.10, 95% CI, 1.02-1.18, p < 0.05). As one component of PSQI, short sleep duration was associated with hypertension prevalence only in Chinese male subjects, but this association disappeared after the further adjustment of the other components of PSQI that measured the qualitative aspect of sleep.
Association between sleep status and hypertension prevalence in Chinese adults varied by age and sex. Sleep should be measured qualitatively and quantitatively when investigating its association with hypertension.
仅通过睡眠时间来评估睡眠是不够的。这项横断面研究旨在调查自我报告的包含定性和定量方面的整体睡眠状况与中国成年人高血压患病率之间的潜在关联。
本研究共纳入5461名受试者(其中4076名男性),并以45岁为分界值将其分为两组。所有受试者的睡眠状况均使用标准匹兹堡睡眠质量指数(PSQI)进行评估。在本研究中,高血压定义为血压≥140/90 mmHg。
在调整基本心血管特征后,多因素逻辑回归结果表明,睡眠状况(定义为睡眠时间和睡眠质量的综合测量)与两个年龄组男性的高血压患病率相关(比值比(OR)= 1.11,95%置信区间(CI),1.07 - 1.15,p < 0.05;OR = 1.12,95% CI,1.08 - 1.15,p < 0.05)以及45岁及以下女性的高血压患病率相关(OR = 1.10,95% CI,1.02 - 1.18,p < 0.05)。作为PSQI的一个组成部分,短睡眠时间仅与中国男性受试者的高血压患病率相关,但在进一步调整测量睡眠定性方面的PSQI其他组成部分后,这种关联消失。
中国成年人的睡眠状况与高血压患病率之间的关联因年龄和性别而异。在研究睡眠与高血压的关联时,应从定性和定量两方面对睡眠进行测量。