He Jie, He Quan
The First Affiliated Hospital of Chongqing Medical University, CN.
Glob Heart. 2022 Feb 21;17(1):10. doi: 10.5334/gh.1100. eCollection 2022.
This study aimed to evaluate the association between sleep duration and hypertension among adults in southwest China.
Baseline variables were collected from a representative sample of 20,053 adults aged 23-98 years in southwest China who received physical examinations from January 2019 to December 2020. All participants were categorized into either a hypertension group or a non-hypertension group. Sleep duration was classified as short (<6 h/day), normal (6-8 h/day),or long (>8 h/day). Baseline variables were compared between individuals with and without hypertension by rank-sum tests for two independent samples or χ tests for nonparametric data. Multivariate logistic regression analysis was performed to evaluate the association between sleep duration and hypertension.
The overall incidence of hypertension was 51.2%. Unadjusted analysis showed that the risk of hypertension was higher in individuals with short (<6h/day) or long (>8h/day) sleep durations compared with those with a normal (6-8 h/day) sleep duration. The risk of hypertension was significantly increased by 30.1% in participants with a long (>8h/day) sleep duration compared with those with a normal (6-8h/day) sleep duration (OR = 1.301, < 0.010, 95%CI = 1.149-1.475). The risk of hypertension was also increased by 1.1% in participants with a short (<6h/day) sleep duration compared with participants with a normal (6-8h/day) sleep duration, but the difference was not significant (OR = 1.011, = 0.849, 95%CI = 0.905-1.129). After fully adjusting for confounding factors (model 4), the risk of hypertension was increased significantly (by 25%) in individuals with a short (<6h/day) sleep duration (OR = 1.25, = 0.02, 95%CI = 1.036-1.508) but not in those with a long (>8h/day) sleep duration (17.5% increase) compared with participants with a normal (6-8h/day) sleep duration (OR = 1.175, = 0.144, 95%CI = 0.946-1.460).
The results of this study indicate that a short (<6h/day) sleep duration is related to an increased risk of hypertension, suggesting that sleep helps to protect against hypertension.
本研究旨在评估中国西南部成年人的睡眠时间与高血压之间的关联。
从2019年1月至2020年12月在中国西南部接受体检的20053名年龄在23 - 98岁的成年人的代表性样本中收集基线变量。所有参与者被分为高血压组或非高血压组。睡眠时间分为短（<6小时/天）、正常（6 - 8小时/天）或长（>8小时/天）。通过两独立样本的秩和检验或对非参数数据的χ检验比较有高血压和无高血压个体之间的基线变量。进行多因素逻辑回归分析以评估睡眠时间与高血压之间的关联。
高血压的总体发病率为51.2%。未调整分析显示，与睡眠时间正常（6 - 8小时/天）的个体相比，睡眠时间短（<6小时/天）或长（>8小时/天）的个体患高血压的风险更高。与睡眠时间正常（6 - 8小时/天）的个体相比，睡眠时间长（>8小时/天）的参与者患高血压的风险显著增加30.1%（OR = 1.301，<0.010，95%CI = 1.149 - 1.475）。与睡眠时间正常（6 - 8小时/天）的参与者相比，睡眠时间短（<6小时/天）的参与者患高血压的风险也增加了1.1%，但差异不显著（OR = 1.011，= 0.849，95%CI = 0.905 - 1.129）。在对混杂因素进行完全调整后（模型4），与睡眠时间正常（6 - 8小时/天）的参与者相比，睡眠时间短（<6小时/天）的个体患高血压的风险显著增加（25%）（OR = 1.25，= 0.02，95%CI = 1.036 - 1.508），而睡眠时间长（>8小时/天）的个体患高血压的风险增加（17.5%）但差异不显著（OR = 1.175），= 0.144，95%CI = 0.946 - 1.460）。
本研究结果表明，睡眠时间短（<6小时/天）与高血压风险增加有关，提示睡眠有助于预防高血压。
