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《动物卫生法》中一类疫病控制措施的评估:猪瘟

Assessment of the control measures of the category A diseases of Animal Health Law: Classical Swine Fever.

作者信息

Nielsen Søren Saxmose, Alvarez Julio, Bicout Dominique Joseph, Calistri Paolo, Canali Elisabetta, Drewe Julian Ashley, Garin-Bastuji Bruno, Gonzales Rojas José Luis, Gortázar Schmidt Christian, Herskin Mette, Michel Virginie, Miranda Chueca Miguel Ángel, Padalino Barbara, Pasquali Paolo, Sihvonen Liisa Helena, Spoolder Hans, Ståhl Karl, Velarde Antonio, Viltrop Arvo, Winckler Christoph, Gubbins Simon, Stegeman Jan Arend, Antoniou Sotiria-Eleni, Aznar Inma, Broglia Alessandro, Lima Eliana, Van der Stede Yves, Zancanaro Gabriele, Roberts Helen Clare

出版信息

EFSA J. 2021 Jul 21;19(7):e06707. doi: 10.2903/j.efsa.2021.6707. eCollection 2021 Jul.

Abstract

EFSA received a mandate from the European Commission to assess the effectiveness of some of the control measures against diseases included in the Category A list according to Regulation (EU) 2016/429 on transmissible animal diseases ('Animal Health Law'). This opinion belongs to a series of opinions where these control measures will be assessed, with this opinion covering the assessment of control measures for Classical swine fever (CSF). In this opinion, EFSA and the AHAW Panel of experts review the effectiveness of: (i) clinical and laboratory sampling procedures, (ii) monitoring period and (iii) the minimum radii of the protection and surveillance zones, and the minimum length of time the measures should be applied in these zones. The general methodology used for this series of opinions has been published elsewhere; nonetheless, details of the model used for answering these questions are presented in this opinion as well as the transmission kernels used for the assessment of the minimum radius of the protection and surveillance zones. Several scenarios for which these control measures had to be assessed were designed and agreed prior to the start of the assessment. Here, several recommendations are given on how to increase the effectiveness of some of the sampling procedures. Based on the average length of the period between virus introduction and the reporting of a CSF suspicion, the monitoring period was assessed as non-effective. In a similar way, it was recommended that the length of the measures in the protection and surveillance zones were increased from 15 to 25 days in the protection zone and from 30 to 40 days in the surveillance zone. Finally, the analysis of existing Kernels for CSF suggested that the radius of the protection and the surveillance zones comprise 99% of the infections from an affected establishment if transmission occurred. Recommendations provided for each of the scenarios assessed aim to support the European Commission in the drafting of further pieces of legislation, as well as for plausible ad hoc requests in relation to CSF.

摘要

欧洲食品安全局(EFSA)收到欧盟委员会的授权,根据关于可传播动物疾病的(EU)2016/429号法规(《动物卫生法》),评估针对A类清单中所列疾病的一些控制措施的有效性。本意见属于一系列将对这些控制措施进行评估的意见之一,本意见涵盖对经典猪瘟(CSF)控制措施的评估。在本意见中,EFSA和动物卫生与福利专家小组审查了以下方面的有效性:(i)临床和实验室采样程序;(ii)监测期;(iii)保护和监测区的最小半径,以及这些措施应在这些区域应用的最短时间。用于这一系列意见的一般方法已在其他地方发表;尽管如此,本意见中还是介绍了用于回答这些问题的模型细节,以及用于评估保护和监测区最小半径的传播核心。在评估开始之前,设计并商定了必须对这些控制措施进行评估的几种情景。在此,就如何提高某些采样程序的有效性提出了若干建议。根据病毒引入与报告CSF疑似病例之间的平均时间长度,评估监测期无效。同样,建议将保护和监测区措施的时长在保护区从15天增加到25天,在监测区从30天增加到40天。最后,对CSF现有传播核心的分析表明,如果发生传播,保护和监测区的半径应涵盖受影响场所99%的感染病例。针对所评估的每种情景提供的建议旨在支持欧盟委员会起草进一步的立法,以及应对与CSF相关的合理临时请求。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd58/8294054/8d8f55941590/EFS2-19-e06707-g002.jpg

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