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输入性疟疾的复发(作者译)

[Recrudescence of imported malaria (author's transl)].

作者信息

Lapierre J, Holler C, Tourte-Schaefer C, Lebas-Saison E, Ancelle T

出版信息

Nouv Presse Med. 1977 Nov 19;6(39):3625-6.

PMID:343066
Abstract

In the light of two recent cases of severe central nervous system malaria due to neglect in chemoprophylaxis, the authors report the very marked recrudescence in imported malaria and draw attention to the frequency of cases due to P. falciparum, the agent of malignant tertian fever and of malignant episodes. The necessity of early diagnosis in such cases is mentioned, together with the treatment of simple malaria and, in particular, of malignant varieties. In order to be effective, chemoprophylaxis must be begun immediately following arrival in an endemic area, continued regularly throughout the stay there and continued for 2 months after leaving. The blood of former malaria suffers, in order to avoid the risks of transfusion malaria, should be used only after seroimmunological studies have demonstrated the absence of anti-malaria antibodies.

摘要

鉴于最近两起因化学预防疏忽导致的严重中枢神经系统疟疾病例,作者报告了输入性疟疾的显著复发情况,并提请注意恶性三日热和恶性发作病原体恶性疟原虫所致病例的频率。文中提到了此类病例早期诊断的必要性,以及单纯性疟疾尤其是恶性疟疾的治疗方法。为了有效预防,化学预防必须在抵达流行地区后立即开始,在整个停留期间定期持续进行,并在离开后持续2个月。为避免输血疟疾风险,曾患疟疾者的血液应仅在血清免疫学研究证明无抗疟疾抗体后使用。

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