Marte Furment Marlene, Antigua Jimenez Sandra, Pabolu Sangeetha
Internal Medicine Department, Saint Peter's University Hospital/Rutgers Robert Wood Johnson Medical School Program, New Brunswick, NJ, USA.
Department of Health Sciences, Instituto Tecnologico de Santo Domingo, Santo Domingo, Dominican Republic.
Case Rep Rheumatol. 2021 Jun 30;2021:5518541. doi: 10.1155/2021/5518541. eCollection 2021.
The diagnosis of giant cell arteritis (GCA) when presenting with atypical features such as stroke is very challenging. Only 0.17% of first-ever strokes are caused by GCA, a life-threatening condition when left untreated. Very few cases have been reported on giant cell arteritis leading to acute stroke due to vertebral artery dissection. We present a case of a 76-year-old female with no medical history who presented with sudden onset right visual loss and left hemiparesis. She had been initially treated for acute stroke and upon further workup was found to have left vertebral artery dissection. She had erythrocyte sedimentation rate (ESR) of 71 mm/h, and bilateral temporal artery biopsy was consistent with giant cell arteritis. Patient received high doses of methylprednisolone which resolved her hemiparesis, but her vision loss did not improve. Stroke in the presence of significant involvement of vertebral arteries should raise suspicion of GCA especially if classic symptoms preceded stroke event. High clinical suspicion is required to prevent delay in diagnosis and treatment.
巨细胞动脉炎(GCA)在表现出如中风等非典型特征时的诊断极具挑战性。首次中风仅有0.17%是由GCA引起的,若不治疗,这是一种危及生命的疾病。关于巨细胞动脉炎导致椎动脉夹层引起急性中风的病例报道极少。我们报告一例76岁无病史女性,她突然出现右眼视力丧失和左侧偏瘫。她最初接受了急性中风治疗,进一步检查发现有左侧椎动脉夹层。她的红细胞沉降率(ESR)为71mm/h,双侧颞动脉活检符合巨细胞动脉炎。患者接受了大剂量甲泼尼龙治疗,偏瘫症状得以缓解,但视力丧失未改善。当椎动脉严重受累时出现中风,应怀疑GCA,尤其是在中风事件之前出现典型症状时。需要高度的临床怀疑以防止诊断和治疗的延误。