Dogra Shruti, Ahuja Arvind, Bhardwaj Minakshi, Sardana Rohan, Goel Hemant
Atal Bihari Vajpayee Institute of Medical Sciences, Dr Ram Manohar Lohia Hospital, New Delhi, India.
Autops Case Rep. 2021 May 6;11:e2021259. doi: 10.4322/acr.2021.259. eCollection 2021.
Androgen secreting adrenocortical carcinoma (ACC) is a very rare disease with a poor prognosis. Approximately 80% of tumors are functional, most commonly secreting glucocorticoids. We herewith report a case of a huge functional ACC of the right adrenal gland in a 33-year-old female who presented with complaints of hirsutism, amenorrhea and an abdominal lump. On abdominal examination a large lump was palpable in the right hypochondrium reaching up to the umbilicus. Contrast-enhance computed tomography (CECT) revealed a mass in the right suprarenal region. The tumor measured 29 cm × 20 cm × 12 cm and weighed 7.8 kg, the largest reported case of ACC in the world to the best of our knowledge.
分泌雄激素的肾上腺皮质癌（ACC）是一种非常罕见的疾病，预后较差。约80%的肿瘤具有功能性，最常见的是分泌糖皮质激素。我们在此报告一例33岁女性巨大功能性右肾上腺ACC病例，该患者主诉多毛、闭经和腹部肿块。腹部检查时，可在右季肋部触及一个大肿块，向上达脐部。增强计算机断层扫描（CECT）显示右肾上腺区域有一肿块。肿瘤大小为29 cm×20 cm×12 cm，重7.8 kg，据我们所知，是世界上报道的最大的ACC病例。
