Kakiuchi Toshihiko, Takamori Ayako, Matsuo Muneaki
Department of Pediatrics, Faculty of Medicine, Saga University, Saga, Japan.
Clinical Research Center, Saga University Hospital, Saga, Japan.
Front Pediatr. 2021 Jul 8;9:697200. doi: 10.3389/fped.2021.697200. eCollection 2021.
Developmental disorders and high () infection rates have been reported. This study aimed to examine the prevalence of in a special needs school where all students had developmental disorders in Japan. In 2017, third-grade junior high school and second- and third-grade high school students attending a special needs school with developmental disorders were enrolled. Participants of Saga Prefecture's test and treat project, which comprised third-grade junior high school students not from special needs school, were assigned to the control group. In the control group, positive results were 3.18% (228/7,164) students. Similarly, in developmental disorder group, positive results were 6.80% (13/191) students. For the developmental disorder and control groups, this present examination sensitivity was 7.03% (13/185), specificity was 96.76% (6,815/7,043), positive predictive value was 5.39% (13/241), negative predictive value was 97.54% (6,815/6,987), Likelihood ratio of a positive result 2.17 and Odds ratio was 2.26 (95% confidence interval: 1.27-4.03, = 0.005). The prevalence of infection was significantly higher in adolescents with developmental disorders than in typically developing adolescents.
已报告发育障碍和高（）感染率。本研究旨在调查日本一所所有学生都有发育障碍的特殊需求学校中的（）患病率。2017年，招募了一所患有发育障碍的特殊需求学校的初中三年级以及高中二年级和三年级学生。来自佐贺县检测与治疗项目、并非来自特殊需求学校的初中三年级学生被分配到对照组。对照组中，（）检测呈阳性的学生比例为3.18%（228/7164）。同样，发育障碍组中，（）检测呈阳性的学生比例为6.80%（13/191）。对于发育障碍组和对照组，本次检测的灵敏度为7.03%（13/185），特异度为96.76%（6815/7043），阳性预测值为5.39%（13/241），阴性预测值为97.54%（6815/6987），阳性结果似然比为2.17，比值比为2.26（95%置信区间：1.27 - 4.03，P = 0.005）。患有发育障碍的青少年中的（）感染患病率显著高于发育正常的青少年。
