全球范围内采用 H. pylori 检测-治疗根除疗法的趋势与胃癌预防策略
World trends for H. pylori eradication therapy and gastric cancer prevention strategy by H. pylori test-and-treat.
机构信息
Fellowship Training Center, Medical Education Center, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Department of Gastroenterology, National Hospital Organization Tokyo Medical Center, 2-5-1 Higashigaoka, Meguro-ku, Tokyo, 152-8902, Japan.
出版信息
J Gastroenterol. 2018 Mar;53(3):354-361. doi: 10.1007/s00535-017-1407-1. Epub 2017 Nov 14.
Helicobacter pylori-associated gastritis leads to the development of gastric cancer. Kyoto global consensus report on H. pylori gastritis recommended H. pylori eradication therapy to prevent gastric cancer. To manage H. pylori infection, it is important to choose the appropriate regimen considering regional differences in resistance to clarithromycin and metronidazole. Quinolones and rifabutin-containing regimens are useful as third- and fourth-line rescue therapies.
幽门螺杆菌相关性胃炎可导致胃癌的发生。京都全球共识报告推荐对幽门螺杆菌胃炎进行根除治疗以预防胃癌。为了管理幽门螺杆菌感染，考虑到克拉霉素和甲硝唑耐药的地区差异，选择合适的方案很重要。含喹诺酮类和利福布汀的方案可作为三线和四线挽救治疗方案。
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