Kwiatkowski Carol F, Andrews David Q, Birnbaum Linda S, Bruton Thomas A, DeWitt Jamie C, Knappe Detlef R U, Maffini Maricel V, Miller Mark F, Pelch Katherine E, Reade Anna, Soehl Anna, Trier Xenia, Venier Marta, Wagner Charlotte C, Wang Zhanyun, Blum Arlene
Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina 27695, United States.
Environmental Working Group, Washington, D.C. 20009, United States.
Environ Sci Technol Lett. 2020 Aug 11;7(8):532-543. doi: 10.1021/acs.estlett.0c00255. Epub 2020 Jun 30.
This commentary presents a scientific basis for managing as one chemical class the thousands of chemicals known as PFAS (per- and polyfluoroalkyl substances). The class includes perfluoroalkyl acids, perfluoroalkylether acids, and their precursors; fluoropolymers and perfluoropolyethers; and other PFAS. The basis for the class approach is presented in relation to their physicochemical, environmental, and toxicological properties. Specifically, the high persistence, accumulation potential, and/or hazards (known and potential) of PFAS studied to date warrant treating all PFAS as a single class. Examples are provided of how some PFAS are being regulated and how some businesses are avoiding all PFAS in their products and purchasing decisions. We conclude with options for how governments and industry can apply the class-based approach, emphasizing the importance of eliminating non-essential uses of PFAS, and further developing safer alternatives and methods to remove existing PFAS from the environment.
本评论文章为将数千种被称为全氟辛烷磺酸（全氟和多氟烷基物质）的化学品作为一类化学品进行管理提供了科学依据。这类化学品包括全氟烷基酸、全氟烷基醚酸及其前体；含氟聚合物和全氟聚醚；以及其他全氟辛烷磺酸。分类方法的依据是基于它们的物理化学、环境和毒理学特性。具体而言，迄今为止所研究的全氟辛烷磺酸具有高持久性、积累潜力和/或危害（已知和潜在的），这使得将所有全氟辛烷磺酸作为一个单一类别来对待是合理的。文中给出了一些全氟辛烷磺酸如何受到监管的例子，以及一些企业如何在其产品和采购决策中避免使用所有全氟辛烷磺酸。我们最后提出了政府和行业如何应用基于类别的方法的选项，强调消除全氟辛烷磺酸非必要用途以及进一步开发更安全的替代品和从环境中去除现有全氟辛烷磺酸的方法的重要性。
