Safer Consumer Products Program, California Department of Toxic Substances Control, Sacramento, California, USA.
Environ Health Perspect. 2021 Feb;129(2):25001. doi: 10.1289/EHP7431. Epub 2021 Feb 17.
Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are a group of manmade chemicals containing at least one fully fluorinated carbon atom. The widespread use, large number, and diverse chemical structures of PFAS pose challenges to any sufficiently protective regulation, emissions reduction, and remediation at contaminated sites. Regulating only a subset of PFAS has led to their replacement with other members of the class with similar hazards, that is, regrettable substitutions. Regulations that focus solely on perfluoroalkyl acids (PFAAs) are ineffective, given that nearly all other PFAS can generate PFAAs in the environment.
In this commentary, we present the rationale adopted by the State of California's Department of Toxic Substances Control (DTSC) for regulating PFAS as a class in certain consumer products.
We at the California DTSC propose regulating certain consumer products if they contain any member of the class of PFAS because: ) all PFAS, or their degradation, reaction, or metabolism products, display at least one common hazard trait according to the California Code of Regulations, namely environmental persistence; and ) certain key PFAS that are the degradation, reaction or metabolism products, or impurities of nearly all other PFAS display additional hazard traits, including toxicity; are widespread in the environment, humans, and biota; and will continue to cause adverse impacts for as long as any PFAS continue to be used. Regulating PFAS as a class is thus logical, necessary, and forward-thinking. This technical position may be helpful to other regulatory agencies in comprehensively addressing this large class of chemicals with common hazard traits. https://doi.org/10.1289/EHP7431.
全氟烷基和多氟烷基物质(PFAS)是一组人工合成化学品,至少含有一个完全氟化的碳原子。PFAS 的广泛使用、数量众多和化学结构多样,对任何充分的保护监管、减排和受污染场地修复都构成了挑战。只对 PFAS 的一部分进行监管导致了它们被该类中具有相似危害的其他成员所取代,也就是说,令人遗憾的替代。仅关注全氟烷基酸(PFAAs)的法规是无效的,因为几乎所有其他 PFAS 都可以在环境中生成 PFAAs。
在这篇评论中,我们介绍了加利福尼亚州毒物管制部(DTSC)在某些消费品中对 PFAS 进行分类监管的基本原理。
我们加利福尼亚州 DTSC 提议对含有任何 PFAS 类别的某些消费品进行监管,因为:)所有 PFAS 或其降解、反应或代谢产物,根据加利福尼亚法规,都显示出至少一个共同的危害特征,即环境持久性;)某些关键的 PFAS 是几乎所有其他 PFAS 的降解、反应或代谢产物或杂质,显示出其他危害特征,包括毒性;在环境、人类和生物群中广泛存在;并且只要任何 PFAS 继续被使用,就会继续造成不利影响。因此,将 PFAS 作为一个类别进行监管是合理的、必要的和前瞻性的。这一技术立场可能有助于其他监管机构全面解决具有共同危害特征的这一大类化学品。https://doi.org/10.1289/EHP7431。