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北欧创伤中心穿透性腹部损伤的选择性非手术治疗:NordiPen 研究。

Selective non-operative management of penetrating abdominal injuries at Northern European trauma centers: the NordiPen Study.

机构信息

Division of Acute Care Surgery, Department of Surgery, North Estonia Medical Centre, Tallinn, Estonia.

Department of Surgery, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia.

出版信息

Eur J Trauma Emerg Surg. 2022 Jun;48(3):2023-2027. doi: 10.1007/s00068-021-01749-2. Epub 2021 Jul 26.

DOI:10.1007/s00068-021-01749-2
PMID:34309723
Abstract

PURPOSE

A selective nonoperative management (SNOM) of penetrating abdominal injuries (PAI) is a standard of care in numerous established trauma centers. However, available evidence supporting SNOM of PAI in European settings remains scarce. Thus, we performed a multi-center study at selected Northern European trauma centers to investigate the management and outcomes of PAI. We hypothesized that despite a low number of penetrating injuries in included trauma centers, SNOM is successfully utilized with outcomes comparable with trauma centers with a high number of PAI.

METHODS

All adult patients admitted to participating trauma centers in the Northern European region with PAI between 1/2015 and 12/2016 were retrospectively reviewed. Primary outcomes were mortality and success rate of SNOM.

RESULTS

Overall, 119 patients were included. Median age was 38 (28-47) years. SNOM was initiated in 55 patients (46.0%) with 94.5% success rate. Three patients (5.5%) failed SNOM and had a delayed laparotomy with one gastric injury, one small bowel injury and one patient with a bleeding from mesentery. Overall mortality of the cohort was 5.0%. However, all patients in the SNOM group survived. Higher median ISS, median Abbreviated Injury Scale score of the abdomen, rate of combined anterior and posterior wounds, rate of in-hospital complications and longer hospital length of stay were observed in the immediate laparotomy group compared to the SNOM group.

CONCLUSIONS

SNOM of PAI is a safe practice even in regions with a low prevalence of penetrating injuries. The outcomes in our study are comparable with results from trauma centers treating larger numbers of patients with PAI.

摘要

目的

在许多已建立的创伤中心,选择性非手术治疗(SNOM)穿透性腹部损伤(PAI)是一种标准的治疗方法。然而,在欧洲环境中支持 PAI 的 SNOM 的可用证据仍然很少。因此,我们在北欧选定的创伤中心进行了一项多中心研究,以调查 PAI 的管理和结果。我们假设,尽管纳入的创伤中心穿透性损伤数量较少,但 SNOM 仍能成功使用,且结果与 PAI 数量较高的创伤中心相当。

方法

回顾性分析了 2015 年 1 月至 2016 年 12 月期间北欧参与的创伤中心收治的所有成年 PAI 患者。主要结局是死亡率和 SNOM 的成功率。

结果

共有 119 名患者纳入研究。中位年龄为 38(28-47)岁。55 名患者(46.0%)开始进行 SNOM,成功率为 94.5%。3 名患者(5.5%)SNOM 失败,行延迟剖腹术,其中 1 例胃损伤,1 例小肠损伤,1 例肠系膜出血。该队列的总死亡率为 5.0%。然而,SNOM 组的所有患者均存活。与 SNOM 组相比,立即剖腹组的中位 ISS、腹部损伤严重程度评分、前后联合伤口率、院内并发症发生率和住院时间均较长。

结论

即使在穿透性损伤发生率较低的地区,PAI 的 SNOM 也是一种安全的治疗方法。我们的研究结果与治疗更多 PAI 患者的创伤中心的结果相当。

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