先天性非进行性肌病中核糖体蛋白合成的改变。
Altered ribosomal protein synthesis in congenital non-progressive myopathy.
作者信息
Pöche H, Kattner E
机构信息
Neurologische Klinik, Freie Universität Berlin.
出版信息
Klin Wochenschr. 1987 Dec 1;65(23):1139-41. doi: 10.1007/BF01734835.
PMID:3431033
Abstract
Ribosomes isolated from fibroblasts, muscle tissues, and blood cells of a patient with congenital non-progressive myopathy were used for in vitro measurement of protein synthesis in a heterologous poly(U)-directed polyphenylalanine synthesis system. The activity of ribosomes obtained from the patient was 35% lower than that in normal controls.
摘要
从一名先天性非进行性肌病患者的成纤维细胞、肌肉组织和血细胞中分离出核糖体，用于在异源多聚尿苷酸指导的聚苯丙氨酸合成系统中体外测量蛋白质合成。从患者体内获得的核糖体活性比正常对照组低35%。
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