Peitsch W
Zentrum Chirurgie, Klinik für Allgemeinchirurgie der Universität, Göttingen.
Langenbecks Arch Chir. 1987;372:173-9. doi: 10.1007/BF01297812.
Routine use of H2 receptor blockers in the therapy of chronic gastroduodenal ulcers reduced the number of ulcer operations. The ulcer recurrence rate in postpyloric and duodenal ulcer seems to be lower after highly selective vagotomies than during long term maintenance treatment, prepyloric ulcers are treated best by gastric vagotomy and antrectomy. In the absence of risk factors perforated gastroduodenal ulcers are treated better by definitive surgery (suture plus vagotomy) than by simple suture.
在慢性胃十二指肠溃疡治疗中常规使用H2受体阻滞剂减少了溃疡手术的数量。幽门后和十二指肠溃疡在高选择性迷走神经切断术后的溃疡复发率似乎低于长期维持治疗期间，幽门前溃疡最好通过胃迷走神经切断术和胃窦切除术治疗。在没有危险因素的情况下，穿孔性胃十二指肠溃疡通过确定性手术（缝合加迷走神经切断术）比单纯缝合治疗效果更好。
