Andersen D
Scand J Gastroenterol Suppl. 1985;110:89-92. doi: 10.3109/00365528509095837.
The need for surgical intervention in duodenal ulcer disease will undoubtedly decrease in the years to come. Occasional failure of medical treatment and persistent doubts about the long-term safety of anti-ulcer drugs will continue to make operation the treatment of choice for some patients, however. Long-term medical treatment and surgery can be considered equally acceptable options for most patients. When operation is considered necessary, parietal cell vagotomy fits the requirements of a modern surgical method better than other techniques. The effective medical treatment now available makes postoperative recurrence of ulcer less important than before and lack of postoperative symptoms has replaced fear of recurrent ulceration as the main concern in the value judgement of both doctors and patients.
在未来几年，十二指肠溃疡疾病的手术干预需求无疑会减少。然而，药物治疗偶尔的失败以及对抗溃疡药物长期安全性的持续疑虑，仍会使手术成为一些患者的首选治疗方式。对大多数患者而言，长期药物治疗和手术可被视为同样可接受的选择。当认为有必要进行手术时，壁细胞迷走神经切断术比其他技术更符合现代手术方法的要求。现有的有效药物治疗使溃疡术后复发不像以前那么重要，并且术后无症状已取代对复发性溃疡的恐惧，成为医生和患者价值判断中的主要关注点。
