Patel Dinesh K
Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, Naini, Prayagraj 211007, Uttar Pradesh, India.
Drug Metab Lett. 2021;14(2):117-125. doi: 10.2174/1872312814666210726112910.
Plants and their derived products have been used in the traditional system of medicine for the treatment of various forms of human disorders since very ancient times. In the traditional system of medicine and modern allopathic medicine, numerous phytoconstituents have been used for the preparation of various types of formulation. Flavonoidal class phytochemicals are the main active phytoconstituents of plants, fruit, vegetables and beverages. Flavonoidal class phytochemicals are more referred as "nutraceuticals" due to their important pharmacological activities in the mammalian body.
In order to understand the beneficial health effects of flavonoidal class chemical, the present work summarized the health beneficial aspects of pectolinarin. Present work summarized the medicinal importance, pharmacological activities and analytical aspects of pectolinarin with various experimental models and advance analytical methods. However, all the collected scientific information's have been analyzed in the present work for their health beneficial potential.
From the analysis of all the collected scientific information in the present work, it was found that pectolinarin is an important phytochemical present in numerous medicinal plants but especially found in Cirsium japonicum, which is an important medicinal herb of Korea, China and Japan. Pharmacological activities data analysis signified the health beneficial potential of pectolinarin for their anti-rheumatoid arthritis, analgesic, anti-inflammatory, hepatoprotective, anti-diabetic, anti-tumor, anti-dengue, antiviral, neuroprotective and antidepressant activity. However, the effectiveness of pectolinarin in central nervous system, bone, liver and cancerous disorders have been also reported in the literature. Analysis of present scientific information revealed the health beneficial potential of pectolinarin in modern medicine due to their numerous pharmacological activities in different parts of biological systems. Due to their biological importance in food and human health, a better understanding of their biological activities indicates their potentials as therapeutic agents.
Scientific data of the present work signified the biological potential and therapeutic benefit of pectolinarin.
自古以来,植物及其衍生产品就被用于传统医学体系中,以治疗各种人类疾病。在传统医学体系和现代对抗疗法医学中,众多植物成分已被用于制备各种类型的制剂。黄酮类植物化学物质是植物、水果、蔬菜和饮料中的主要活性植物成分。由于黄酮类植物化学物质在哺乳动物体内具有重要的药理活性,因此更常被称为“营养保健品”。
为了了解黄酮类化合物的有益健康作用,本研究总结了pectolinarin的健康益处。本研究总结了pectolinarin的药用重要性、药理活性以及使用各种实验模型和先进分析方法的分析方面。然而,本研究对所有收集到的科学信息进行了分析,以评估其潜在的健康益处。
通过对本研究中所有收集到的科学信息进行分析,发现pectolinarin是众多药用植物中存在的一种重要植物化学物质,尤其在日本蓟中含量丰富,日本蓟是韩国、中国和日本的一种重要草药。药理活性数据分析表明,pectolinarin具有抗类风湿性关节炎、镇痛、抗炎、保肝、抗糖尿病、抗肿瘤、抗登革热、抗病毒、神经保护和抗抑郁活性等潜在的健康益处。然而,文献中也报道了pectolinarin在中枢神经系统、骨骼、肝脏和癌症疾病方面的有效性。对现有科学信息的分析揭示了pectolinarin在现代医学中的潜在健康益处,因为它们在生物系统的不同部位具有多种药理活性。由于它们在食品和人类健康中的生物学重要性,更好地了解它们的生物活性表明了它们作为治疗剂的潜力。
本研究的科学数据表明了pectolinarin的生物学潜力和治疗益处。