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补骨脂素对人类健康并发症的潜在治疗特性:药用重要性和药理活性综述

The Potential Therapeutic Properties of Prunetin against Human Health Complications: A Review of Medicinal Importance and Pharmacological Activities.

作者信息

Patel Kanika, Patel Dinesh Kumar

机构信息

Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, Uttar Pardesh, India.

出版信息

Drug Metab Bioanal Lett. 2022;15(3):166-177. doi: 10.2174/2949681015666220912104743.

Abstract

BACKGROUND

Flavonoids are polyphenolic compounds found to be present in nature and abundant in flowers and fruits. Flavonoidal class phytochemicals have gained interest in the scientific field because of their important pharmacological activities. Several scientific studies have revealed anti-bacterial, anti-oxidant, anti-fungal, analgesic, anti-viral, anti-inflammatory, anti-tumor, anti-parasitic and anti-allergic activities of flavonoidal class phytochemicals. Prunetin is an O-methylated isoflavone that belongs to the phytochemical phytoestrogen class, found to be present in licorice, red cherry, soybean and legumes.

METHODS

Biological potential and pharmacological activities of prunetin have been investigated in the present work through scientific data analysis of numerous scientific research works. Numerous literature databases have been searched in order to collect the scientific information on prunetin in the present work. Pharmacological activities of prunetin have been investigated in the present work through literature data analysis of different scientific research works. Scientific data have been collected from Google Scholar, Google, PubMed, Science Direct and Scopus. Analytical data on prunetin has been collected from literature sources and analyzed in the present work.

RESULTS

Scientific data analysis revealed the biological importance of prunetin in medicine. Prunetin was found to be present in the pea, peach, Oregon cherry, skimmed cheese, cheese, cow kefir and goat kefir. Prunetin is also present in the Prunus avium, Andira surinamensis, Butea superba, Dalbergia sympathetica, Ficus nervosa, Pterospartum tridentatum and Pycnanthus angolensis. Pharmacological data analysis revealed the biological importance of prunetin on bone disorders, cancers, especially hepatocellular carcinoma, urinary bladder cancer, gastric cancer, ovarian cancer, human airway, gut health and enzymes. Scientific data analysis revealed biological effectiveness of prunetin for their angiogenic effects, anti-inflammatory, anti-oxidant, antimicrobial, estrogenic and vasorelaxant potential. Analytical data revealed the importance of modern analytical techniques for qualitative and quantitative analysis of prunetin in the scientific fields.

CONCLUSION

Scientific data analysis in the present investigation revealed the biological importance and pharmacological activities of prunetin in medicine.

摘要

背景

黄酮类化合物是自然界中存在的多酚类化合物,在花和果实中含量丰富。黄酮类植物化学物质因其重要的药理活性而在科学领域受到关注。多项科学研究揭示了黄酮类植物化学物质具有抗菌、抗氧化、抗真菌、止痛、抗病毒、抗炎、抗肿瘤、抗寄生虫和抗过敏活性。樱黄素是一种O-甲基化异黄酮,属于植物化学物质植物雌激素类别,存在于甘草、红樱桃、大豆和豆类中。

方法

在本研究中,通过对众多科研工作的科学数据分析,对樱黄素的生物学潜力和药理活性进行了研究。为了收集本研究中关于樱黄素的科学信息,检索了众多文献数据库。通过对不同科研工作的文献数据分析,在本研究中对樱黄素的药理活性进行了研究。科学数据从谷歌学术、谷歌、PubMed、科学Direct和Scopus收集。关于樱黄素的分析数据从文献来源收集并在本研究中进行分析。

结果

科学数据分析揭示了樱黄素在医学中的生物学重要性。发现樱黄素存在于豌豆、桃子、俄勒冈樱桃、脱脂奶酪、奶酪、牛奶发酵乳和山羊发酵乳中。樱黄素也存在于欧洲甜樱桃、苏里南安德利亚木、紫铆、交感黄檀、多脉榕、三叉叶翅豆和安哥拉锥花中。药理数据分析揭示了樱黄素在骨骼疾病、癌症,尤其是肝细胞癌、膀胱癌、胃癌、卵巢癌、人类气道、肠道健康和酶方面的生物学重要性。科学数据分析揭示了樱黄素在血管生成作用、抗炎、抗氧化、抗菌、雌激素和血管舒张潜力方面的生物学有效性。分析数据揭示了现代分析技术在科学领域对樱黄素进行定性和定量分析的重要性。

结论

本研究中的科学数据分析揭示了樱黄素在医学中的生物学重要性和药理活性。

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