Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, U.K.
Biosci Rep. 2021 Aug 27;41(8). doi: 10.1042/BSR20210953.
The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which started in late 2019, has caused huge social and economic losses. A growing number of investigators are focusing on understanding the interaction of SARS-CoV-2 with host cellular processes to find therapeutic approaches. New data suggest that lipid metabolism may play a significant role in regulating the response of immune cells like macrophages to viral infection, thereby affecting the outcome of the disease. Therefore, understanding the role of lipid metabolism could help develop new therapeutic approaches to mitigate the social and economic cost of coronavirus disease 2019 (COVID-19).
严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）的全球大流行始于 2019 年末，已造成巨大的社会和经济损失。越来越多的研究人员专注于了解 SARS-CoV-2 与宿主细胞过程的相互作用，以寻找治疗方法。新数据表明，脂代谢可能在调节巨噬细胞等免疫细胞对病毒感染的反应方面发挥重要作用，从而影响疾病的结果。因此，了解脂代谢的作用可能有助于开发新的治疗方法，以减轻 2019 年冠状病毒病（COVID-19）的社会和经济成本。
