Facultad de Ciencias Agrarias y Veterinarias-UCASAL, INTA EEA Salta, RN 68 Km 172, 4403 Cerrillos, Salta, Argentina; CONICET, INTA EEA Salta, RN 68 Km 172, 4403 Cerrillos, Salta, Argentina.
INTA-Balcarce, INTA EEA Salta, RN 68 Km 172, 4403 Cerrillos, Salta, Argentina.
Toxicon. 2021 Sep;200:134-139. doi: 10.1016/j.toxicon.2021.07.012. Epub 2021 Jul 24.
Hairy vetch (Vicia villosa) poisoning in cattle is characterized by a systemic granulomatous inflammatory response that resembles a type-IV hypersensitivity reaction. Hairy vetch toxicity has been described in cattle worldwide. The aim of this paper was to describe 10 outbreaks of hairy vetch poisoning in cattle studied at INTA EEA Salta and INTA EEA Balcarce, Argentina, from 2004 to 2019. Clinical signs included weakness, pyrexia, dermatitis, alopecia, and progressive weight loss, which leads to death over a clinical course of approximately two weeks. A total of 12 necropsies were performed and tissue samples were collected for histopathology. The main gross changes were observed in skin, lymph nodes, liver, heart, spleen and kidneys. Other tissues, such as pancreas, thyroid, and adrenal glands, were also affected. Histological lesions consisted of multifocal to diffuse granulomatous inflammation in those organs. The toxicity of hairy vetch has been described in several countries of the world. In Argentina, the use of hairy vetch as a cover crop has become common in some regions during the past years. The data suggest that hairy vetch poisoning is an important disease in cattle. More studies are needed to contribute with further information.
猪毛菜（Vicia villosa）中毒的特征是全身性肉芽肿性炎症反应，类似于 IV 型超敏反应。猪毛菜毒性已在世界范围内的牛中被描述。本文的目的是描述 2004 年至 2019 年在阿根廷 INTA EEA Salta 和 INTA EEA Balcarce 研究的 10 起牛猪毛菜中毒暴发。临床症状包括虚弱、发热、皮炎、脱毛和进行性体重减轻，导致临床病程约两周后死亡。共进行了 12 次剖检，并采集组织样本进行组织病理学检查。主要的大体变化发生在皮肤、淋巴结、肝脏、心脏、脾脏和肾脏。胰腺、甲状腺和肾上腺等其他组织也受到影响。组织学病变包括这些器官的多灶性至弥漫性肉芽肿性炎症。猪毛菜的毒性已在世界上几个国家被描述。在阿根廷，过去几年，一些地区已将猪毛菜作为覆盖作物使用。数据表明，猪毛菜中毒是牛的一种重要疾病。需要进一步研究以提供更多信息。
