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减重手术后的糖尿病缓解

Diabetes remission after bariatric surgery.

作者信息

Chumakova-Orin Maryna, Vanetta Carolina, Moris Dimitrios P, Guerron Alfredo D

机构信息

Department of Surgery, Duke University, Durham, NC 27705, United States.

出版信息

World J Diabetes. 2021 Jul 15;12(7):1093-1101. doi: 10.4239/wjd.v12.i7.1093.

Abstract

Over the last decade, obesity rates have continued to rise in the United States as well as worldwide and are showing no signs of slowing down. This rise is in parallel with the increasing rates of type 2 diabetes mellitus (T2DM). Given the association between obesity and T2DM and their strong correlation with increased morbidity and mortality in addition to healthcare expenditure, it is important to recognize the most effective ways to combat them. Thus, we performed a review of literature that focused on assessing the outcomes of T2DM following bariatric surgery. Available evidence suggests that bariatric surgery provides better T2DM resolution in obese patients when compared to best medical management alone. Additionally, Biliopancreatic diversion with duodenal switch as well as Roux-en-Y gastric bypass have demonstrated higher rates of T2DM resolution when compared with other bariatric procedures.

摘要

在过去十年中,美国以及全球的肥胖率持续上升,且没有放缓的迹象。这种上升与2型糖尿病(T2DM)发病率的增加同步。鉴于肥胖与T2DM之间的关联,以及它们除了医疗保健支出外还与发病率和死亡率增加密切相关,认识到对抗它们的最有效方法很重要。因此,我们对文献进行了综述,重点评估减肥手术后T2DM的治疗效果。现有证据表明,与单纯最佳药物治疗相比,减肥手术能使肥胖患者的T2DM得到更好的缓解。此外,与其他减肥手术相比,胆胰转流十二指肠转位术以及Roux-en-Y胃旁路术的T2DM缓解率更高。

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