Instituto de Enfermedades Tropicales, Universidad Nacional Toribio Rodríguez de Mendoza de Amazonas (UNTRM), Amazonas, Peru.
Instituto de Investigación en Ganadería y Biotecnología, Universidad Nacional Toribio Rodríguez de Mendoza de Amazonas (UNTRM), Amazonas, Peru.
Parasitol Int. 2021 Dec;85:102428. doi: 10.1016/j.parint.2021.102428. Epub 2021 Jul 27.
Fascioliasis is a zoonotic disease caused by parasites of the genus Fasciola spp. which cause an important loss to the livestock industry. The objectives of this study were: to estimate the prevalence of fascioliasis in three provinces of Amazonas, to evaluate possible risk factors of infection in cattle and to genetically characterize the Fasciola haplotypes circulating in this area. According to the results the prevalence of fascioliasis in cattle was 90.13% (712/790). Odds ratio results showed a significant association between fascioliasis and the Brown Swiss breed (OR = 2.62; 95% CI: 1.57-4.35; p < 0.001), and with female cattle older than 30 months (OR = 1.71; 95% CI: 1.05-2.79; p < 0.031). According to the molecular genetic studies using the gene marker NAD1, six haplotypes of Fasciola hepatica were found in the 35 infected livers collected. The results obtained in this study are concerning due to the high prevalence presented and it reveals the necessity of a continuing monitoring because of the high risk of transmission to humans.
片形吸虫病是一种由片形科寄生虫引起的人畜共患疾病，给畜牧业造成了重大损失。本研究的目的是：估计亚马逊三个省的片形吸虫病流行情况，评估牛感染的可能危险因素，并对该地区流行的片形吸虫单倍型进行基因特征分析。结果显示，牛的片形吸虫病流行率为 90.13%（712/790）。比值比结果表明，片形吸虫病与瑞士褐牛品种（OR=2.62；95%CI：1.57-4.35；p<0.001）和30 个月以上的母牛（OR=1.71；95%CI：1.05-2.79；p<0.031）之间存在显著关联。根据使用 NAD1 基因标记进行的分子遗传学研究，在 35 个受感染的肝脏中发现了 6 种肝片形吸虫单倍型。由于高流行率，本研究的结果令人担忧，这表明需要持续监测，因为存在向人类传播的高风险。
