Jeyaratnam J, Lee J, Lee H P, Phoon W O
Department of Community, Occupational and Family Medicine, Faculty of Medicine, National University of Singapore.
Scand J Work Environ Health. 1987 Dec;13(6):524-6. doi: 10.5271/sjweh.2006.
A retrospective cohort study of 279 Chinese fishermen in Singapore was undertaken to examine the possibility of an elevated incidence of stomach cancer. The fishermen as a group had a greater than twofold excess in stomach cancer relative to Chinese men of similar age and over the same calendar years in Singapore, but the difference was not statistically significant. On further examination it was revealed that the four stomach cancer cases were observed among the subgroup of divers. The standardized incidence ratio for the divers was 4.3, which was significantly greater than unity. There was no evidence of an increased risk for cancer of any other site (lung, nasopharynx and liver) in this cohort. Dietary factors are suggested as a possible explanation for the observation of an increased risk for stomach cancer among fishermen, but larger studies are required to test this hypothesis.
对新加坡279名中国渔民进行了一项回顾性队列研究,以检验胃癌发病率升高的可能性。与新加坡同一年份、年龄相仿的中国男性相比,渔民群体的胃癌发病率高出两倍多,但差异无统计学意义。进一步检查发现,在潜水员亚组中观察到4例胃癌病例。潜水员的标准化发病率为4.3,显著高于1。该队列中没有证据表明其他任何部位(肺、鼻咽和肝脏)患癌风险增加。饮食因素被认为可能是渔民胃癌风险增加这一观察结果的解释,但需要更大规模的研究来验证这一假设。