Suppr超能文献

儿科透析和肾移植患者在自然灾害或人为灾害后的管理。

Management of pediatric dialysis and kidney transplant patients after natural or man-made disasters.

机构信息

Department of Pediatric Nephrology, Cerrahpasa School of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.

Department of Pediatric Nephrology, Istanbul Training and Research Hospital, Istanbul, Turkey.

出版信息

Pediatr Nephrol. 2023 Feb;38(2):315-325. doi: 10.1007/s00467-022-05734-8. Epub 2022 Oct 4.

Abstract

Pediatric patients on kidney replacement therapy (KRT) are among the most vulnerable during large-scale disasters, either natural or man-made. Hemodialysis (HD) treatments may be impossible because of structural damage and/or shortage of medical supplies, clean water, electricity, and healthcare professionals. Lack of peritoneal dialysis (PD) solutions and increased risk of infectious/non-infectious complications may make PD therapy challenging. Non-availability of immunosuppressants and increased risk of infections may result in graft loss and deaths of kidney transplant recipients. Measures to mitigate these risks must be considered before, during, and after the disaster including training of staff and patients/caregivers to cope with medical and logistic problems. Soon after a disaster, if the possibility of performing HD or PD is uncertain, patients should be directed to other centers, or the duration and/or number of HD sessions or the PD prescription adapted. In kidney transplant recipients, switching among immunosuppressants should be considered in case of non-availability of the medications. Post-disaster interventions target treating neglected physical and mental problems and also improving social challenges. All problems experienced by pediatric KRT patients living in the affected area are applicable to displaced patients who may also face extra risks during their travel and also at their destination. The need for additional local, national, and international help and support of non-governmental organizations must be anticipated and sought in a timely manner.

摘要

儿科患者在接受肾脏替代治疗(KRT)时,无论是在自然或人为灾害中,都属于最脆弱的群体之一。由于结构损坏和/或医疗用品、清洁水、电力和医疗保健专业人员的短缺,血液透析(HD)治疗可能无法进行。缺乏腹膜透析(PD)溶液以及感染/非感染性并发症风险增加,可能使 PD 治疗变得具有挑战性。免疫抑制剂的不可用以及感染风险的增加可能导致移植肾失功和移植受者死亡。必须在灾害发生前、发生中和发生后考虑减轻这些风险的措施,包括对工作人员和患者/护理人员进行培训,以应对医疗和后勤问题。如果在灾难发生后,进行 HD 或 PD 的可能性不确定,应指导患者转至其他中心,或调整 HD 治疗的持续时间和/或次数或 PD 处方。在肾移植受者中,如果药物不可用,应考虑在免疫抑制剂之间进行转换。灾难后的干预措施旨在治疗被忽视的身心问题,并改善社会挑战。受灾地区的儿科 KRT 患者所经历的所有问题都适用于流离失所的患者,这些患者在旅行中和到达目的地时也可能面临额外的风险。必须及时预料到并寻求额外的当地、国家和国际帮助和支持,以及非政府组织的支持。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验