Ogata T, Kodama M, Ishimaru T
Laboratory of Marine Biological Chemistry, School of Fisheries Sciences, Kitasato University, Iwate, Japan.
Toxicon. 1987;25(9):923-8. doi: 10.1016/0041-0101(87)90154-1.
Many clones of Protogonyaulax tamarensis were collected from Ofunato Bay in the same season and cultured under the same conditions. The toxicity of the cultured cells of these clones was remarkably different from each other (maximum of 100-fold). Significant differences (maximum of 20-fold) in toxicity of cultured cells were also observed among subclones isolated from a single clonal culture. It is unlikely that this variation in toxicity among subclones is due to mutation during culture. From these observations we suggest that toxin production in P. tamarensis is not a hereditary characteristic.
在同一季节从大船渡湾采集了许多塔玛亚历山大藻克隆体，并在相同条件下进行培养。这些克隆体的培养细胞毒性彼此差异显著（最大相差100倍）。从单一克隆培养物分离出的亚克隆体之间，培养细胞的毒性也存在显著差异（最大相差20倍）。亚克隆体之间这种毒性差异不太可能是由于培养过程中的突变所致。基于这些观察结果，我们认为塔玛亚历山大藻产生毒素并非遗传特性。
