Obstetrics and Gynecology, University "Magna Graecia" of Catanzaro, Catanzaro, Italy.
Hum Reprod. 2021 Aug 18;36(9):2421-2428. doi: 10.1093/humrep/deab181.
Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility; however, whether women with PCOS and spontaneous or drug-induced ovulatory cycles have the same reproductive potential as non-PCOS controls is a matter of debate. In the present opinion paper, the author takes the opportunity to summarize the collective evidence supporting the hypothesis of reduced fertility potential in women with PCOS, regardless of ovulatory status, and speculate that reduced reproductive potential may be caused by altered oocytes, embryo and endometrial competence, and infertility-related co-morbidities as well as an increased risk of pregnancy complications.
多囊卵巢综合征（PCOS）是无排卵性不孕的最常见原因；然而，无论 PCOS 患者是否存在自发或药物诱导的排卵周期，她们是否具有与非 PCOS 对照组相同的生殖潜能，这是一个有争议的问题。在本观点文章中，作者借此机会总结了支持 PCOS 妇女无论排卵状态如何生育潜能降低的综合证据，并推测降低的生育潜能可能是由卵子、胚胎和子宫内膜功能改变以及与不孕相关的合并症以及妊娠并发症风险增加引起的。
