Department of Ophthalmology, Shijiazhuang People's Hospital, No. 365 Jianhua Street, Shijiazhuang city, Hebei Province, People's Republic of China.
Int Ophthalmol. 2021 Dec;41(12):4217-4223. doi: 10.1007/s10792-021-01988-7. Epub 2021 Jul 31.
To comparatively analyze differences in macular choroidal thickness and volume in primary chronic angle-closure glaucoma (PACG) eyes.
Thirty-one PACG patients were sequentially selected for this case-control study. Thirty-one eyes with PACG were included in group A, 31 fellow eyes were included in group B, and group C included 67 normal eyes. Enhanced-depth imaging optical coherence tomography (EDI-OCT) was used to measure choroidal thickness and volume.
The choroidal thicknesses and volumes of the central subfield macula (CSM), nasal inner macula (NIM), temporal inner macula (TIM), inferior inner macula (IIM), temporal outer macula (TOM), inferior outer macula (IOM), and mean macula (MM) in group A were all higher than those in group C (P < 0.05). The choroidal thicknesses and volumes of the NIM, superior inner macula (SIM), IIM, nasal outer macula (NOM), and MM in group B were all higher than those in group C (P < 0.05). No statistically significant differences were found between groups A and B (P > 0.05). The choroidal thicknesses of different macular regions in group A were not correlated with the mean defect (MD).
Increased macular choroidal thickness may be a common anatomical characteristic of PACD eyes. Macular choroidal thickness is not a good marker for assessing PACG severity.
比较原发性慢性闭角型青光眼（PACG）患眼的黄斑脉络膜厚度和体积差异。
本病例对照研究连续选择了 31 例 PACG 患者。将 31 只 PACG 眼纳入 A 组，31 只对侧眼纳入 B 组，67 只正常眼纳入 C 组。应用增强深度成像光学相干断层扫描（EDI-OCT）测量脉络膜厚度和体积。
A 组中央小凹区（CSM）、鼻侧内中区（NIM）、颞侧内中区（TIM）、下方内中区（IIM）、颞侧外中区（TOM）、下方外中区（IOM）和平均黄斑区（MM）的脉络膜厚度和体积均高于 C 组（P<0.05）。B 组的 NIM、上方内中区（SIM）、IIM、鼻侧外中区（NOM）和 MM 的脉络膜厚度和体积均高于 C 组（P<0.05）。A 组和 B 组之间无统计学差异（P>0.05）。A 组不同黄斑区的脉络膜厚度与平均缺损（MD）无相关性。
黄斑脉络膜厚度增加可能是 PACG 眼的共同解剖特征。黄斑脉络膜厚度不是评估 PACG 严重程度的良好标志物。
