Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Institute for Minority Health Research, University of Illinois at Chicago, Chicago, IL, USA.
Public Health Nutr. 2021 Dec;24(18):6272-6280. doi: 10.1017/S1368980021002949. Epub 2021 Aug 2.
To investigate associations of egg intake with blood pressure (BP) and the role of dietary variables and other macro- and micro-nutrients in the association.
We used cross-sectional data for the USA as part of the INTERnational study on MAcro/micronutrients and blood Pressure (INTERMAP). INTERMAP was surveyed between 1996 and 1999, including four 24-h dietary recalls, two 24-h urine collections and eight measurements of systolic BP and diastolic BP (SBP, DBP). Average egg intake (g/d) was calculated. Multivariable linear regression models were used to estimate the association between egg intake (per each 50 g/d or per quintile) and BP. The roles of dietary variables and other macro- and micro-nutrients in this association were also investigated.
In the USA.
In total, 2195 US INTERMAP men and women aged 40-59 years.
Participants were 50 % female, 54 % non-Hispanic White and 16 % non-Hispanic Black. Mean egg intake (sd) in men and women was 30·4(29·8) and 21·6(20·5) g/d, respectively. Adjusting for demographics, socio-economics, lifestyle and urinary Na:K excretion ratios, we found non-linear associations with BP in non-obese women (P-quadratic terms: 0·004 for SBP and 0·035 for DBP).The associations remained after adjusting for dietary variables, macro/micro nutrients or minerals. Dietary cholesterol was highly correlated with egg intake and may factor in the association. No association was found in obese women and in obese or non-obese men.
Egg intake was non-linearly associated with SBP and DBP in non-obese women, but not in obese women or men. Underlying mechanisms require additional study regarding the role of obesity and sex.
研究鸡蛋摄入量与血压（BP）的关联，并探讨饮食变量和其他宏量及微量营养素在其中的作用。
我们使用了美国作为 INTERnational 研究宏量/微量营养素与血压（INTERMAP）的一部分的横断面数据。INTERMAP 于 1996 年至 1999 年进行了调查，包括四次 24 小时饮食回忆、两次 24 小时尿液收集和 8 次收缩压和舒张压（SBP、DBP）测量。平均鸡蛋摄入量（g/d）进行了计算。采用多变量线性回归模型来估计鸡蛋摄入量（每增加 50 g/d 或每五分位组）与 BP 之间的关联。还研究了饮食变量和其他宏量及微量营养素在这种关联中的作用。
美国。
共有 2195 名年龄在 40-59 岁的美国 INTERMAP 男性和女性参与者。
参与者中 50%为女性，54%为非西班牙裔白人，16%为非西班牙裔黑人。男性和女性的平均鸡蛋摄入量（标准差）分别为 30.4(29.8)和 21.6(20.5)g/d。在调整了人口统计学、社会经济学、生活方式和尿钠钾排泄比后，我们发现非肥胖女性的 BP 与鸡蛋摄入量呈非线性关联（SBP 的 P 二次项：0.004，DBP：0.035）。在调整了饮食变量、宏量/微量营养素或矿物质后，这种关联仍然存在。饮食胆固醇与鸡蛋摄入量高度相关，可能是这种关联的一个因素。在肥胖女性以及肥胖或非肥胖男性中未发现这种关联。
鸡蛋摄入量与非肥胖女性的 SBP 和 DBP 呈非线性关联，但在肥胖女性和男性中则没有。需要进一步研究肥胖和性别的作用，以了解潜在机制。
