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MRI联合CT在胆管癌患者中的辅助诊断及影像特征

The Auxiliary Diagnosis and Imaging Characteristics of MRI Combined with CT in Patients with Cholangiocarcinoma.

作者信息

Li Jing, Yu Yuanlin, He Qing

机构信息

Department of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, China.

Department of Radiotherapy, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, China.

出版信息

J Oncol. 2021 Jul 16;2021:2790958. doi: 10.1155/2021/2790958. eCollection 2021.

DOI:10.1155/2021/2790958
PMID:34335752
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8315873/
Abstract

BACKGROUND

Patients with cholangiocarcinoma (CCA) have poor prognosis and high mortality. Therefore, early detection and early diagnosis are extremely important to control the development of CCA. This study aims to explore the diagnostic effect in patients with CCA and imaging characteristics of MRI combined with CT.

METHODS

109 patients with suspected CCA underwent CT and MRI before diagnosis. The examination results were compared with the "gold standard." ROC curve was drawn to analyze the diagnostic efficacy of MRI combined with CT for CCA patients.

RESULTS

The diagnosis rate of suspected CCA patients was 95.41%. The diagnostic coincidence rate of CT and MRI examination was 89.42% and 92.31%, respectively. The diagnostic coincidence rate of MRI combined with CT examination was 100.00%. The number of CT delayed enhancement, peripheral bile duct dilatation, and hepatic capsular depression were more than those of MRI. The number of circular enhancement cases in the CT group was less than that in the MRI group. ROC curve results showed that the sensitivity and specificity of MRI combined with CT for the diagnosis of CCA patients were higher than those of MRI or CT alone.

CONCLUSION

MRI combined with CT has high diagnostic sensitivity and specificity and can provide imaging evidence for the clinical diagnosis and treatment of CCA.

摘要

背景

胆管癌(CCA)患者预后较差,死亡率高。因此,早期发现和早期诊断对于控制CCA的发展极为重要。本研究旨在探讨MRI联合CT对CCA患者的诊断效果及影像学特征。

方法

109例疑似CCA患者在诊断前行CT和MRI检查。将检查结果与“金标准”进行比较。绘制ROC曲线,分析MRI联合CT对CCA患者的诊断效能。

结果

疑似CCA患者的诊断率为95.41%。CT和MRI检查的诊断符合率分别为89.42%和92.31%。MRI联合CT检查的诊断符合率为100.00%。CT延迟强化、外周胆管扩张和肝包膜凹陷的例数多于MRI。CT组环形强化病例数少于MRI组。ROC曲线结果显示,MRI联合CT诊断CCA患者的敏感性和特异性高于单独使用MRI或CT。

结论

MRI联合CT具有较高的诊断敏感性和特异性,可为CCA的临床诊断和治疗提供影像学依据。

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本文引用的文献

1
A case report of cholangiocarcinoma combined with moderately differentiated gastric adenocarcinoma.胆管癌合并中分化胃腺癌病例报告
Medicine (Baltimore). 2019 Jul;98(30):e16332. doi: 10.1097/MD.0000000000016332.
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Mechanisms of Dysfunction in the Aging Vasculature and Role in Age-Related Disease.衰老血管功能障碍的机制及其在与年龄相关疾病中的作用。
Circ Res. 2018 Sep 14;123(7):825-848. doi: 10.1161/CIRCRESAHA.118.312563.
肝内胆管癌伴胃转移误诊为原发性胃癌:1例报告及文献复习
Front Oncol. 2022 Sep 5;12:997735. doi: 10.3389/fonc.2022.997735. eCollection 2022.